DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and Zbtb43

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001012094.1	Gene:	Zbtb43 / 311872	RGDID:	1310287	Length:	503	Species:	Rattus norvegicus

Alignment Length:	446	Identity:	89/446 - (19%)
Similarity:	147/446 - (32%)	Gaps:	160/446 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFF--DAVLSNYASERDPIIIMKDVT 77
            |.:....:|...:|..|||::..:|.:.:||:.||.|.|.:|  ..:|.|  |.|   |::.||.
  Rat    53 STILQKLNQQRQQGQLCDVSIVVQGHIFQAHKAVLAASSPYFCDQVLLKN--SRR---IVLPDVM 112

  Fly    78 FAEV-KCLIEFMYKGEINVEHSSLPSLLKTADDLK----IKGLAEVTWRDDEDGPPPPMA----- 132
            ...| :.::.|.|.|.:.:....:.|.|..|..|:    :....||.     :|.|..:.
  Rat   113 NPRVFENILLFSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVL-----EGNPTVLCQKLNH 172

  Fly   133 AAEFHSPPRS----LAESY------------AQDLILQHQQQQQQGPAAPPLNLHSSAALLERDR 181
            .::..||..|    ||||:            ||:|                           ||.
  Rat   173 GSDHQSPSSSNYNGLAESFELGSGGHTDFPKAQEL---------------------------RDG 210

  Fly   182 ERERERDRERLSPGMEGVLGRMPVMTPLTGASGSAGVGSVSGGTSLEGVAPVEHFLGPKRKRGRP 246
            |.|.|..::.||                         ..|:....|...:..||
  Rat   211 ENEEESTKDELS-------------------------SQVTEHEYLPSNSSTEH----------- 239

  Fly   247 PLDDAYDVFNVRKLAQYAANLEPAQRAYLETARHFTEEPPLAAHAASMASPPAACPPKQRQRLRH 311
                       .:|:...|:.:..:.....|..|:|.  ||       .|.|:..|   .:|..|
  Rat   240 -----------DRLSTEMASQDGEEGTNDSTEFHYTR--PL-------YSKPSIMP---HRRWIH 281

  Fly   312 QQQQQQQLLQSESSDQEQPAAGQDWSNLEPNGSATPKLLSDGDANKQETEGGDESLPAVLTTASS 376
            .:.::          .|||     |..::.:.:.....:|: ..|..:|:          .:|..
  Rat   282 VKPER----------LEQP-----WDGMDVHAAYDEHQVSE-SVNTMQTD----------HSAQP 320

  Fly   377 SGTKKLEKIGERRERHGKLRHARRLYEKSGEDEVDPPKEEPDELPQPVEEIENEHL 432
            ||.::..:|.|::.......||    |.|..|      |:.|.....:||...|.|
  Rat   321 SGAEEEFQIVEKKVEVEFDEHA----EGSNYD------EQVDFYGSSMEEFSGEKL 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	28/103 (27%)
		BTB	32..121	CDD:197585	27/95 (28%)
		HTH_psq	587..622	CDD:283007
Zbtb43	NP_001012094.1	BTB_POZ_ZBTB43	44..164	CDD:349536	32/120 (27%)
		C2H2 Zn finger	412..430	CDD:275368
		C2H2 Zn finger	438..458	CDD:275368
		zf-H2C2_2	450..473	CDD:404364
		C2H2 Zn finger	466..483	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910