DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and Zbtb37

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001100661.1	Gene:	Zbtb37 / 304918	RGDID:	1308731	Length:	504	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	86/414 - (20%)
Similarity:	143/414 - (34%)	Gaps:	101/414 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERDPIIIMKDVTFAEVKCLIE 86
            :||..:|..||:.:..:||..|||:|||.|.|.:|...:|........|.::|:.|..|.  |:.
  Rat    25 NQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQ--LLS 87

  Fly    87 FMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPPMAAAEFHSPPRSLAESYAQDL 151
            |.|.|.|.::.:.:.|.|..|..|::                            :.:.:...|.|
  Rat    88 FCYTGRICLQLADIISYLTAASFLQM----------------------------QHIIDKCTQIL 124

  Fly   152 ILQHQQQQQQGPAAPPLNLHSSAALLERDRERERERDRE--RLSPGMEGVLGRMPVMTPLTGASG 214
            ...|.:          :|:....|.|.:.|.:..||..|  |::|.:...|      :|...||.
  Rat   125 EGIHFK----------INVAEVEAELSQTRTKHPERPPESHRVTPNLTRSL------SPRHNASK 173

  Fly   215 SAGVGSVSGGTSLEGVAPVEHFLGPK------RKRGRPPLDDAYDVFNVRKLAQYAANLEPAQRA 273
            ....|.||....:..::|.|....|:      ...||.|      :..:.:..|:
  Rat   174 GNWRGQVSAVLDIRELSPPEESTSPQIIEQSSDVEGREP------ILRINRAGQW---------- 222

  Fly   274 YLETARHFTEEPPLAAHAASMASPPAACPPKQRQRLRHQQQQQQQLLQSESSDQEQPAAGQDWSN 338
            |:||.  ..::.|.:.               ...|:......:.:.|:.....:.|| :|:|.|:
  Rat   223 YVETG--IADQGPQSG---------------DEVRVLGAVHIKTENLEEWLGPENQP-SGEDGSS 269

  Fly   339 LEPNGSATPKLLSDGDANKQETEGGDESLPAVLTTASSSGTKKLEKIGERRERHGKLRHARRLYE 403
            .|...:........|..       |.||.     |..|||.|.........:|.........:.|
  Rat   270 AEEVAAMVIDTTGHGSV-------GQESY-----TLGSSGAKVARPTSSEVDRFSPSGSVVSMTE 322

  Fly   404 KSGEDEVDPPK-EEPDELPQPVEE 426
            :.......|.: :||.:|...|||
  Rat   323 RHRARSESPGRMDEPKQLSSQVEE 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	30/95 (32%)
		BTB	32..121	CDD:197585	26/88 (30%)
		HTH_psq	587..622	CDD:283007
Zbtb37	NP_001100661.1	BTB_POZ_ZBTB37	9..131	CDD:349531	33/145 (23%)
		C2H2 Zn finger	377..397	CDD:275368
		zf-H2C2_2	389..414	CDD:404364
		zf-C2H2	403..425	CDD:395048
		C2H2 Zn finger	405..425	CDD:275368
		zf-H2C2_2	418..440	CDD:404364
		DUF4764	<429..>497	CDD:406387
		C2H2 Zn finger	433..451	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910