DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and Nacc2

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001094003.1	Gene:	Nacc2 / 296583	RGDID:	1309292	Length:	585	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	72/326 - (22%)
Similarity:	115/326 - (35%)	Gaps:	69/326 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERDPIIIMKDVTFAEVKCLIEFMYKGE 92
            |.:|||::..:||..:|||.||.|.|.:|..:.|  .:.:....:...|..|..:.::.|.|.|:
  Rat    27 GLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFS--GNSKSAFELPGTVPPACFQQILSFCYTGK 89

  Fly    93 INVEHSSLPSLLKTADDLKIKGLAE-----------------VTWRDDEDGPP-------PPMAA 133
            :.:..|....::.||..|:|:.:.|                 ....:|....|       .|..|
  Rat    90 LTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAMIEDASSEPQSPCNQLQPATA 154

  Fly   134 AEFHSPPRSLAESYAQDLILQHQQQQQQGPAAPPLNLHSSAALLERDRERERERDRERLSPGMEG 198
            |...||      |....|:.:.:.:..:.|.|....|.|...|      ....||...::.|..|
  Rat   155 AYATSP------SVPIPLLTRVKHEAMEMPPATGPGLASKRPL------DTGPRDGVAVATGAAG 207

  Fly   199 VLGRMPVMTPLTGASGSAGVGSVSGGTSLEGVAPVEHFLGPKRKRGRPPL--------------- 248
            ..|..|:..|..   ...||.|::  |.:..:..|.:..|.:...|...|
  Rat   208 TPGTAPLKLPRV---SYYGVPSLA--TLIPSIQQVPYPQGERTSPGASSLPTTDSPTSYHNEDED 267

  Fly   249 -DDAYDV--------FNVRKLAQYAANLEPAQRAYLETARHFTEEPPLAAHAASMASPPA-ACPP 303
             |:|||.        ..::....||...:| :...||:.........|.|..||:.|... .|.|
  Rat   268 DDEAYDTMVEEQYGQMYIKATGNYAVQEKP-EPVPLESRSCVLIRRDLVALPASLISQIGYRCHP 331

  Fly   304 K 304
            |
  Rat   332 K 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	26/106 (25%)
		BTB	32..121	CDD:197585	24/105 (23%)
		HTH_psq	587..622	CDD:283007
Nacc2	NP_001094003.1	BTB_POZ_BTBD14A_NAC2	1..131	CDD:349598	26/105 (25%)
		PHA03247	<138..260	CDD:223021	28/138 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	238..269		3/30 (10%)
		BEN	370..447	CDD:214981
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	541..585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I5180
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050