DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and Nacc1

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_006255276.1	Gene:	Nacc1 / 171454	RGDID:	621003	Length:	540	Species:	Rattus norvegicus

Alignment Length:	564	Identity:	109/564 - (19%)
Similarity:	186/564 - (32%)	Gaps:	198/564 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 YHHSNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERDPII----I 72
            :.:|.|:.:..|.| :|.:|||::..:|...:|||.||.|.|::|..:   :.|.|..::    .
  Rat    38 FGNSILECLNEQRL-QGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDL---FNSSRSAVVELPAA 98

  Fly    73 MKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWR----------DDEDGP 127
            ::..:|.::   :.|.|.|.:::.......|:.||..|:|:.:.|....          |.:...
  Rat    99 VQPQSFQQI---LTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLH 160

  Fly   128 PPPMAAAEFHSPPRSLAESYAQDLILQHQQQQQQGPA-APPLNLHSSAALLERDRERERERDRER 191
            |....::|..||       .||.|         ..|| :.||.|.|..       :.|:|.|..:
  Rat   161 PEEAPSSEPQSP-------VAQIL---------GWPACSTPLPLVSRV-------KTEQELDSVQ 202

  Fly   192 LSP--------------GMEGVLG---------------RMPVMTPLTGASGSAGVGSVSGGTSL 227
            .:|              |..|..|               |||  .|::.|:.:|.|..|:.|..:
  Rat   203 CTPMAKRLWDSSQKEAGGSGGNNGSRKMAKFSTPDLAPNRMP--QPVSVATATAAVAVVAVGGCV 265

  Fly   228 EGVAPVEHFLGPKRKRGRPPLDDAYDVFNVRKLAQYAANLEPAQRAYLETARHFTEEPPLAAHAA 292
            .|.:..|        |..|....||                             |.:.|.:
  Rat   266 SGPSMSE--------RTSPGTSSAY-----------------------------TSDSPSS---- 289

  Fly   293 SMASPPAACPPKQRQRLRHQQQQQQQLLQSESSDQEQPA------------AGQDWSNLEPNGSA 345
                             .|.::.:::....|.:|::...            .||....:|    |
  Rat   290 -----------------YHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTVEKVE----A 333

  Fly   346 TPKLLSDGDANKQETEGGDESLPAVLTTASSSGTKKLEKIGERRERHGKLRHARRLYEKSGEDEV 410
            .|:.:.....::........||||.|          :.:||.|  .|.||           .||.
  Rat   334 LPEQVVLESHSRIRVRQDLASLPAEL----------INQIGNR--CHPKL-----------YDEG 375

  Fly   411 DPPKEEPDELPQPVEEIENEHLVANRAE--------SPRPTVVIPASFACKYEGGVTAAGGGSGS 467
            ||.::        :|.:...::...||:        ..|..|::....|..::....|...|:|.
  Rat   376 DPSEK--------LELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGI 432

  Fly   468 GTGSGS-----LGSSYLINEHGM-LMAHEFAPNVASAAATAAVA 505
            .:.:..     |.|..|   |.: .....||||...:...|..|
  Rat   433 RSSTNDPRRKPLDSRVL---HAVKYYCQNFAPNFKESEMNAIAA 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	26/100 (26%)
		BTB	32..121	CDD:197585	23/92 (25%)
		HTH_psq	587..622	CDD:283007
Nacc1	XP_006255276.1	BTB	46..147	CDD:279045	27/107 (25%)
		BTB	57..148	CDD:197585	23/96 (24%)
		BEN	408..486	CDD:214981	15/69 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I5180
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050