DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and pre-lola-G

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001260870.2	Gene:	pre-lola-G / 14462577	FlyBaseID:	FBgn0264817	Length:	436	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	64/340 - (18%)
Similarity:	112/340 - (32%)	Gaps:	118/340 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 AANLEPAQRAYLETARHFTEEPPLAAHAASMASPPAACPPK----------QRQRLRHQQQQ--Q 316
            ||:..|..:..|:||...||.......:..:|:..||..||          .|..|.:.|||  .
  Fly   130 AASFHPRPKYTLKTAASSTEHTTAIPTSVLVANSAAALTPKPQAAVIAEALMRNGLHNFQQQLRA 194

  Fly   317 QQLLQSESSDQEQPAAGQDWSNLEPNGSATP--KLLSDGDANKQETEGGDESLPAVLTTASSSGT 379
            |::|:.:                      ||  ::..:.|.   |..|||           .:.|
  Fly   195 QEILRQQ----------------------TPHRRIKEENDV---EIAGGD-----------ITPT 223

  Fly   380 KKLEKIGERRERHGKLRHARRLYEKSGEDEVDPPKEEPDELPQPVEEIENEHLVANRAESPRPTV 444
            |.||.: .|:::...|||:        |.|.:|.....|:........::.||:..
  Fly   224 KILENL-LRKQQERDLRHS--------ECENEPGYSTEDDEEGRYHAFDDIHLMEQ--------- 270

  Fly   445 VIPASFACKYEGGVTAAGGGSGSGTGSGSLGSSYLINEHG-----MLMAHEFAPNVASAAATAAV 504
                            :||..|:.:|.|...:    |.||     :|.||:...|:....:.
  Fly   271 ----------------SGGKFGNNSGMGMFNA----NAHGGSASSILDAHQAFRNLEFTLSD--- 312

  Fly   505 AVAAAAAAVANASAGNGNGGQDVSGSGTGAAADYPDIKLEDYDAAELRLTNEELSQWQDVIKMDD 569
                        ..|:.:.|...|.:|.|         |:.....|.|...::. :|:..::..:
  Fly   313 ------------YGGSSSNGSTTSPNGIG---------LDGEPVYECRHCGKKY-RWKSTLRRHE 355

  Fly   570 YLAKGRRPQFWEEPF 584
            .:..|.:....:.|:
  Fly   356 NVECGGKEPSHQCPY 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045
		BTB	32..121	CDD:197585
		HTH_psq	587..622	CDD:283007
pre-lola-G	NP_001260870.2	C2H2 Zn finger	338..358	CDD:275368	2/20 (10%)
		zf-H2C2_5	366..389	CDD:290620	1/5 (20%)
		C2H2 Zn finger	368..388	CDD:275368	1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000