DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and AgaP_AGAP008959

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_319710.4	Gene:	AgaP_AGAP008959 / 1279925	VectorBaseID:	AGAP008959	Length:	489	Species:	Anopheles gambiae

Alignment Length:	484	Identity:	118/484 - (24%)
Similarity:	187/484 - (38%)	Gaps:	138/484 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LIRAHRVVLCACSTFFDAVLSNYAS--ERDP-----IIIMKDVTFAE-VKCLIEFMYKGEINVEH 97
            :..||:|:|.|||       .|:|.  ||.|     |.:|.:.|.|: :..|:|||||||::|..
Mosquito     2 VFNAHKVILAACS-------KNFADLFERAPVGTGQICVMLEATSADNMHALLEFMYKGEVHVSQ 59

  Fly    98 SSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPP----MAAAEFHSPPRSLAESYAQDLILQHQQQ 158
            .:|.|.||.|::|::.....:..|.:::....|    ......|...||.|.:.|        .|
Mosquito    60 KALESFLKAAENLQVSHTRGIDLRCEDEAVITPAICVCTGQRTHYRARSFASANA--------SQ 116

  Fly   159 QQQGP-AAPPLNLHSSAALLERDRERERERDRERLSPGMEGVLGRMPVMT-PLTGASGSAGVGSV 221
            ..|.| ..||.:|.|.|.         |.:.|..||..:|.:...:...| .:.|::.|.|.||.
Mosquito   117 PSQSPFHGPPNDLPSPAI---------RRQQRNSLSSSLESINRAVKRETDSIVGSASSGGNGSS 172

  Fly   222 --SGGTSLEGVAPVEHFLGPKRKRGRPPLDDAYDVFNVR-----------------------KLA 261
              |||.:..|.|......|..|..|    :|..:..|.|                       ..:
Mosquito   173 HGSGGGAGAGGATGNAGSGADRGSG----NDRGNRGNDRGGESGGVGGGGGGGGGGGGGGNTPAS 233

  Fly   262 QYAANLEPAQRAYLETARHFTEEPPLAAHAASMASPPAACPPKQRQRLR-----HQQQQQQQLLQ 321
            .::..|:|:  :||                      |.:...::|. ||     ||:..:..:|:
Mosquito   234 SFSPYLQPS--SYL----------------------PGSYENRKRS-LRSPFYEHQEATRDSVLR 273

  Fly   322 --SESSDQEQPAAGQDWSNLEPN---GSATP----KLLSDGDANKQETEGGDESLPAVLTTAS-- 375
              ..|:....|.:|.  .|..|:   .||||    .:.:|.|:.:|.....:.| |:  ||..
Mosquito   274 DGKASAGNGSPVSGS--KNYRPSSSGSSATPTEADTIHTDRDSPQQSNRYENHS-PS--TTHGHG 333

  Fly   376 ----SSGTKKLEKIGERRERHG----KLRHARRLYEKSGEDEVDPPKEEPDELPQPVEEIENEHL 432
                ||.|...|   ||.:.:|    |::|..|...::|.::: ..|.|...:..|:
Mosquito   334 NGPVSSNTMDRE---ERNDHNGSVDHKVKHESREGNEAGAEDL-RVKMEMRPIQSPL-------- 386

  Fly   433 VANRAESPRPTVVIPASFACKYEGGVTAA 461
               |:.:| .|...|..| ...:||:.||
Mosquito   387 ---RSSAP-STPTTPIGF-INVKGGLEAA 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	31/84 (37%)
		BTB	32..121	CDD:197585	31/87 (36%)
		HTH_psq	587..622	CDD:283007
AgaP_AGAP008959	XP_319710.4	BTB	1..86	CDD:197585	32/90 (36%)
		BTB	<3..76	CDD:279045	31/79 (39%)
		C2H2 Zn finger	437..458	CDD:275368
		C2H2 Zn finger	465..482	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920