DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and AgaP_AGAP002303

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_312667.5	Gene:	AgaP_AGAP002303 / 1273665	VectorBaseID:	AGAP002303	Length:	466	Species:	Anopheles gambiae

Alignment Length:	476	Identity:	116/476 - (24%)
Similarity:	166/476 - (34%)	Gaps:	157/476 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LPQQYCLRWKYHHSNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASE 66
            |.||:|:||..|..:|...|.|:.....|.||||||||..:..||:||.||||:|:.:|.....:
Mosquito     8 LSQQFCVRWNSHLGSLGAAFPQVRKPSPFVDVTLACEGHQVHCHRLVLAACSTYFENLLGENPCK 72

  Fly    67 RDPIIIMKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPPM 131
            ...||:.:|:....::.|::||||||:||..:.||.|:|.|:.|||:||.         |....:
Mosquito    73 HPIIILPRDIKLWAIQALVDFMYKGEVNVSQAGLPDLMKCAEVLKIRGLC---------GSDAAL 128

  Fly   132 AAAEFHSPPRSLAESYAQDLILQHQQQQQQGPAAPPLNLHSSAALLERDRERERERDRERLS--- 193
            ...:.|||..|            ||.||||         ||||...:.....|......|.|
Mosquito   129 NLNQVHSPSGS------------HQYQQQQ---------HSSANSSDAGEPVEHAGATARASEGS 172

  Fly   194 -PGMEGVLGRMPVMTPLTGASG-----------------------------SAGVGSVSGGTSLE 228
             .|..|...:...|.....:||                             ..||.|.:|.:..|
Mosquito   173 YAGRHGGQSQSARMQQSNASSGPKRQLLNSLNLQPIDAGIALPHHHHHQQNEDGVHSDNGESGNE 237

  Fly   229 GVAPVEHFL-----------GPKRKRGRPPLD-------DAYDVFNV------------------ 257
            .....|..:           |.:.:.|....|       ..:.:.||
Mosquito   238 MCIKTEDLIIDEDDSGSRQCGDEEELGMDSTDKTGSDLPSEFALANVTCEYELNTQPQAPQDTST 302

  Fly   258 ------------RKLAQYAANLEPAQRAYLE------TARHF----------------------T 282
                        ::.|:|.:..|..|...|:      |.|.:                      :
Mosquito   303 AGRRVRRSEELLQQAAEYVSRGETFQNVSLKFDIPISTIRFYMARKGILPRRKRGRTAMFPCSVS 367

  Fly   283 EEPPLAAHAASMASPPAACPPKQRQRLRHQQQQQQQLLQSESSDQEQPAAGQDWSNLEPNGSATP 347
            ..|.|||......||.::..|:...|.:.||||.:|.|....|     .||...:|.:
Mosquito   368 NRPILAAVDMMAPSPTSSFIPQPTLRDQQQQQQYRQQLSENMS-----IAGTQSANAQ------- 420

  Fly   348 KLLSDGDANKQETEGGDESLP 368
                  .||..:|.|..|.:|
Mosquito   421 ------TANVSQTAGAPERVP 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	43/96 (45%)
		BTB	32..121	CDD:197585	40/88 (45%)
		HTH_psq	587..622	CDD:283007
AgaP_AGAP002303	XP_312667.5	BTB	31..121	CDD:279045	39/89 (44%)
AgaP_AGAP002303	XP_312667.5	BTB	38..121	CDD:197585	38/82 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010