DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and btbd18

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_017951392.1	Gene:	btbd18 / 100498010	-ID:	-	Length:	602	Species:	Xenopus tropicalis

Alignment Length:	462	Identity:	92/462 - (19%)
Similarity:	158/462 - (34%)	Gaps:	135/462 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LRWKYHHSN-LQTMFSQL---LDRGCFCDVTL-ACEGQLIRAHRVVLCACSTFFDAVLSNY--AS 65
            :|.:|.:.. |:|||.||   .:.|.|||||| ..||:.:..|..:|.|||.:...:|::.  .|
Frog     5 VRLRYWNPRLLRTMFLQLQRQQNTGFFCDVTLQGGEGEGVSVHACLLAACSPYLAKLLASVTEVS 69

  Fly    66 ERDP-----------IIIMKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVT 119
            :.|.           |:.:..:....:..|:.:||..|:.|...::..:|:.|..|:|..|..:.
Frog    70 QLDTDSAIQTDCTGHILTVPGIPSCYLLPLVHYMYTSELEVTPENVHGVLEAARRLQIPELEGLR 134

  Fly   120 WRDDEDG--PPPPMAAAEFHSPPRSLAESYAQDLILQHQQQQQQGPAA-----------PPLNLH 171
            .   |.|  ..|.:|        |.|.......:|.|:..:...|...           .|:.:|
Frog   135 L---EGGRLVRPELA--------RKLNRDCFGSVISQYATESGNGKQIFTKEEITSGRNVPVRMH 188

  Fly   172 SSAALLERDRERERERDRERLSPGMEGVLGRMPVMTPLTGASGSAGVGSVSGGTSLEGVAPVEHF 236
            .....:     .|:..::|...|...|.|.|                |.:...:||:|
Frog   189 EQGPCI-----LEKRTNKEHTFPADTGSLLR----------------GKMEASSSLQG------- 225

  Fly   237 LGPKRKRGRPPLDDAYDVFNVRKLAQYAANLEPAQRAYLETARHFTEEPPLAAHAASMASPPAAC 301
                                         |:|   ...||..::.||:                .
Frog   226 -----------------------------NIE---NPLLEITKNPTEK----------------S 242

  Fly   302 PPKQRQRLRHQQQQQQQLLQSESSDQEQPAAGQDWSNLEPNGSATPKLLSDGDANKQ--ETEGGD 364
            .|...|.....::..:...|...:.|...|..|| ..:....|..|.::.:.|..:.  .:|.|.
Frog   243 GPSTVQTCFQSRENYECAFQDSGTTQNVSAINQD-IEMTKLSSEIPLIVLNPDQKRHILVSEHGA 306

  Fly   365 ESLPAVLTTASSSGTKKLEKIGERRERHGKLRHARRLYEKSGEDEVDP-------PKEEPDELPQ 422
            :::|:..|....   |||.|:    :|..|:|.........|:..:.|       .:.|..::||
Frog   307 DTVPSRKTDMQD---KKLFKL----QRAYKVRKETGEQATKGKTNIIPLSRIIKLDRGEKQDMPQ 364

  Fly   423 PVEEIEN 429
            ..|.|:|
Frog   365 MDENIKN 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	31/113 (27%)
		BTB	32..121	CDD:197585	25/102 (25%)
		HTH_psq	587..622	CDD:283007
btbd18	XP_017951392.1	BTB_POZ_BTBD18	17..148	CDD:349602	37/141 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000