DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3726 and Btbd18

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_002729248.1	Gene:	Btbd18 / 100363270	RGDID:	2323370	Length:	724	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	104/498 - (20%)
Similarity:	178/498 - (35%)	Gaps:	146/498 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LQTMFSQL---LDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNY--ASERDPIIIMKDV 76
            |:..|.||   ...|.|||..|..||:.:.||..:|.|||.||...|...  ...|..::.:..:
  Rat    17 LRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLELGGL 81

  Fly    77 TFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPPMAAAEFHSPPR 141
            ....::.|::|:|..|:.|.......:|..|..|::..|..:           .:...:....|:
  Rat    82 KIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETL-----------QLEGGKLVKAPQ 135

  Fly   142 SLAESYAQDLILQHQQQQQQGPAAPPLNLHSSAALLERDRERERERDRERLSPGMEGVLGRMPVM 206
            .          .:..::..|.|:|.|:   |:..::.|.|.|
  Rat   136 G----------RRLNRECLQPPSAAPI---SARVVVPRSRPR----------------------- 164

  Fly   207 TPLTGASGSAGVGSVSGGTSLEGVAPVEHFLGPKRKRGRPPLDDAYDVFNVRK-----LAQYAAN 266
            |||......:.:|:|    .|:.:...|   |..:|...|..|:..|...::|     |.|..::
  Rat   165 TPLPVTQTPSPLGAV----KLKSLGEEE---GAHKKSNLPNADNLSDTLLLKKKARVCLTQERSS 222

  Fly   267 LEPAQR---------------------------------AYLETARH-FTEEPPLAAHAASMASP 297
            ...:||                                 :..:.:.| :|.:|      :||.|.
  Rat   223 SPSSQREGPKENKSNPGSTALPSLYPSVDEQLLPRKIRLSRSKPSPHVYTSKP------SSMLSG 281

  Fly   298 PAACPPKQRQRLRHQQQQQQQLLQSESSDQEQPAAGQDWSNLEPNGSATPKLLSDGDANKQETEG 362
            |::.|....:||..|:...:   .::..|:::|.   :.|.|:    :||   ...|..|  |.|
  Rat   282 PSSMPTAPGRRLWRQRTVSE---ATQGVDKQKPG---EVSTLQ----STP---DPPDVGK--TGG 331

  Fly   363 GDESLPAVLTTASSS------GTKKLEKI--GERRE--RHGKLRHAR---RLYEKSGEDEVDPP- 413
            ..:..|.....||:|      |..||.||  |...|  :...:|:.:   ::.|.|..||  ||
  Rat   332 KKQPSPESRAPASNSVEEGQVGRVKLRKIVNGTCWEVVQEPPIRNTQDSPQILESSDADE--PPG 394

  Fly   414 ----KEEPDELPQPV----EEIENEHL---VANRAESPRPTVV 445
                .....|:|..:    :..||..|   :.:.:.||...||
  Rat   395 TLLSSVNEQEIPARIQLCHDSPENSRLQDILLSASHSPDHPVV 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	29/101 (29%)
		BTB	32..121	CDD:197585	23/90 (26%)
		HTH_psq	587..622	CDD:283007
Btbd18	XP_002729248.1	BTB	24..123	CDD:279045	27/98 (28%)
Btbd18	XP_002729248.1	BTB	35..123	CDD:197585	23/87 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000