DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3726 and Btbd18

DIOPT Version :9

Sequence 1:NP_001284917.1 Gene:CG3726 / 31525 FlyBaseID:FBgn0029824 Length:682 Species:Drosophila melanogaster
Sequence 2:NP_001138572.1 Gene:Btbd18 / 100270744 MGIID:3650217 Length:723 Species:Mus musculus


Alignment Length:505 Identity:100/505 - (19%)
Similarity:170/505 - (33%) Gaps:165/505 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 LQTMFSQL---LDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNY--ASERDPIIIMKDV 76
            |:..|.||   ...|.|||..|..||:.:.||..:|.|||.||...|...  ...|..::.|..:
Mouse    17 LRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLEMGGL 81

  Fly    77 TFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGL-------------------------- 115
            ....::.|::|:|..|:.|.......:|..|..|::..|                          
Mouse    82 KIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNRECLQP 146

  Fly   116 ---AEVTWR--DDEDGPPPPMAAAEFHSP-----PRSLAESYAQDLILQHQQQQQQGPAAPPLNL 170
               |.::.|  ..:..|..|:...:..||     .:||.|              ::| |....||
Mouse   147 PAAAPISARVVGPKSRPQTPLPVTQTPSPLGAVRLKSLGE--------------EEG-AHKKTNL 196

  Fly   171 HSSAALLERDRERERE---RDRERLSPGMEGVLGRMPVMTPLTGASGSAGVGSVSGGTSLEGVAP 232
            .::.:|.:...:::..   ....|.||..:              ..|.....|..|.|:|..:.|
Mouse   197 PNADSLSDTQLKKKARVCLTQESRSSPSSQ--------------REGPKETKSNPGPTALPSLYP 247

  Fly   233 -VEHFLGPKRKRGRPPLDDAYDVFNVRKLAQYAANLEPAQRAYLETARHFTEEPPLAAHAASMAS 296
             |:..|.|::.|                    .:..:|:...|..|             .:|:.|
Mouse   248 SVDEQLLPRKIR--------------------LSRSKPSPHVYTST-------------PSSILS 279

  Fly   297 PPAACPPKQRQRLRHQQQQQQQLLQSESSDQEQPAAGQD-WSNLEPNGSATPKLLSDGDANKQET 360
            .|::.|....:||..|:...:   :::..|:::|...:. .|..:|:....|.      .||:::
Mouse   280 GPSSMPTAPGRRLWRQRTVSK---EAQGVDKQKPGEVRPLQSTPDPSDVGKPA------ENKKQS 335

  Fly   361 EGGDESLPAVLTTASSS------GTKKLEKIGERRERHGKLRHARRLYEKSGEDEVDPPKEEPDE 419
                   |.:....|||      |..||.||               :.....|...:||.....:
Mouse   336 -------PELRAPTSSSVEEGQVGRVKLRKI---------------VNGTCWEVVQEPPLRNTQD 378

  Fly   420 LPQPVE--EIE----------NE-------HLVANRAESPR-PTVVIPAS 449
            .||.:|  ::|          ||       .|..:..|||| ..:::.||
Mouse   379 SPQILEPSDVEEPSGTLLSSVNEQEIPARIQLCQDSPESPRLQDILLSAS 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3726NP_001284917.1 BTB 21..118 CDD:279045 31/130 (24%)
BTB 32..121 CDD:197585 25/119 (21%)
HTH_psq 587..622 CDD:283007
Btbd18NP_001138572.1 BTB_POZ_BTBD18 20..138 CDD:349602 30/117 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 150..176 5/25 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 188..350 39/225 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 370..394 6/23 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 603..637
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 699..723
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000141
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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