DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3726 and zbtb21

DIOPT Version :9

Sequence 1:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001090699.1	Gene:	zbtb21 / 100036678	XenbaseID:	XB-GENE-995449	Length:	1030	Species:	Xenopus tropicalis

Alignment Length:	544	Identity:	97/544 - (17%)
Similarity:	174/544 - (31%)	Gaps:	182/544 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HHSNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERDPIIIMKDVT 77
            |.|::.:..::...:..||||.|....|..|||:.:|.|.|.:|.::.:...:|...:..: |..
Frog    12 HASSMLSALNEERLKEEFCDVLLIVGDQKFRAHKNILAATSEYFQSLFTEKDNESQTVFQL-DFC 75

  Fly    78 FAEV-KCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPPMAAAEFHSPPR 141
            .|:| :.::.::|...|.||.|||.::.:....|.|..|..:..:..:. |.|.:..|||.....
Frog    76 DADVFENVLNYIYSSSIFVEKSSLAAVQELGYSLGINFLTNIVSKTPQT-PFPSIKNAEFKEEDE 139

  Fly   142 SLAES----------YAQDLILQHQQQQQQGPAAPPL----NLHSSAALL-----------ERDR 181
            |.::.          .||:..:.|....:..|..|.|    ..|.:..|:           ||..
Frog   140 SGSQQRSVIVCQNRIEAQERDISHLHHDKSRPLKPSLLPQGKTHGNRPLMRLSEPPNSLLSERKW 204

  Fly   182 ERERERDRERLS----------------------PGMEGVLGR---------------------- 202
            ......|.:.:|                      ||:.|.|.|
Frog   205 RNSYVSDDQGISRSVKRKSTLPQKSFPSLESNDKPGISGCLLRNTSETFEKQMLASVPPSYSSSE 269

  Fly   203 ------------MPV------------MTPLTGASGSAGVGSVSGGT------------------ 225
                        :|:            ...||.::||....:...|.
Frog   270 YPYSSLIRGKESVPIKEEEEENVVYYSKVGLTSSAGSTHQNTDRSGPLVKSLLRRSLSMDSPVPA 334

  Fly   226 -------SLEGV-APVEH-----FLGPKRKRGRPPLDDAYDVFNVRKLAQYAANL-------EPA 270
                   ||||. |.:|:     .:.....:.:..||     .:.|..||...||       :|.
Frog   335 YSHSPDFSLEGTSAMIENCNKAVAIAGFHNQSKTDLD-----LDARDNAQEKCNLKISFVSSKPH 394

  Fly   271 QRAYL-ETARHFTEEPPLAAHAASMASPPAACPPKQRQRLRHQQQQQQQLLQ------SESSDQE 328
            .|..: |...|..:||         .|||:               :..::.:      |:.|:::
Frog   395 SRESIPEKDVHIKKEP---------GSPPS---------------ETSEIFRVTVGDTSQPSNRD 435

  Fly   329 QPAAGQDWSN-----LEPNGSATPKLLSDGDANKQETEGGDESL---PAVLTTASSSGTKKLEKI 385
            .|...::..|     ::....|..::|.......:.....|.:|   ..:|...||......|..
Frog   436 VPIKAEETPNIIKMPIKRKLQADRRMLPSRRVKMKSAISPDATLEEGALILDADSSDSESSRELY 500

  Fly   386 GE----RRERHGKLRHARRLYEKS 405
            ||    |:.:..|.:|..:::..:
Frog   501 GEASESRQNKKFKCKHCLKIFRST 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	27/97 (28%)
		BTB	32..121	CDD:197585	25/89 (28%)
		HTH_psq	587..622	CDD:283007
zbtb21	NP_001090699.1	BTB_POZ_ZBTB21_ZNF295	12..123	CDD:349518	29/111 (26%)
		C2H2 Zn finger	514..535	CDD:275368	1/11 (9%)
		C2H2 Zn finger	637..657	CDD:275368
		zf_C2H2_6	711..738	CDD:408245
		C2H2 Zn finger	875..895	CDD:275370
		C2H2 Zn finger	903..924	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910