Protein Alignment CG12236 and BACH2

DIOPT Version :9

• Sequence 1: NP_727050.1
• Gene: CG12236 / 31523
• FlyBaseID: FBgn0029822
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_024302278.1
• Gene: BACH2 / 60468
• HGNCID: 14078
• Length: 927
• Species: Homo sapiens
• Alignment Length: 583
• Identity: 93/583 - (15%)
• Similarity: 171/583 - (29%)
• Gaps: 211/583 - (36%)

  Fly     4 TQQYSLRWNNY-----------------------------LRHLTYSLDNHRLNDDFVDVSLCVD 39
            |.|.|..||.:                             ..::...|::.|..|...||:|.|:
Human    66 TSQISRNWNVFKSWQSQGVNGMSVDEKPDSPMYVYESTVHCTNILLGLNDQRKKDILCDVTLIVE 130

  Fly    40 GRRIKAHKVVLSSCSSYF-KEIFKENPHPHPVIIFKFIKFEDLNSIIEFMYQGEVNVQQEALQSF 103
            .:..:||:.||::||.|| :.:..:..:...|.:.:.:.......:::|.|..::.:.:|.::..
Human   131 RKEFRAHRAVLAACSEYFWQALVGQTKNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREV 195

  Fly   104 LQTAELLAVQGLTAEEKEKPQIPVAPLISEHKLIKTIPSTIRAVNEQQQQVSNVAQAQTATQTIE 168
            ::.||.|.:..|                                                    |
Human   196 IRCAEFLRMHNL----------------------------------------------------E 208

  Fly   169 IPAATLLQATNASQVPSQVVAAAAAAAAAQQLQVQHQQQQHHHVQTTQIQHIQVQSAPPPQQQQQ 233
            ....:.||....:......|....||.          |:.|...:.:               ..:
Human   209 DSCFSFLQTQLLNSEDGLFVCRKDAAC----------QRPHEDCENS---------------AGE 248

  Fly   234 QQQQQQQQQQQQQQQQQQQSQQQQTTPVQTQHLTITNAVALPAASSVKKRKITFSDDDDNMYTTE 298
            ::.::::....:..:......|....|:..:      |.|:|.|   :|.:....:.|   ..|:
Human   249 EEDEEEETMDSETAKMACPRDQMLPEPISFE------AAAIPVA---EKEEALLPEPD---VPTD 301

  Fly   299 TVDYAVKDEQTIVKTAEMTFLRGAVKMDIPDYIVGEVDDRLSDGATPQTSQDATTAAAQNVAQYS 363
            |.:.:.||..|                ..|.|               :..|.|.|....|.:.:|
Human   302 TKESSEKDALT----------------QYPRY---------------KKYQLACTKNVYNASSHS 335

  Fly   364 SEYEILTESEMEEKYQADADNAEIAIEMTRLLGTASGTPGAGSGQVMEDSGGGSATTGPSTTVSV 428
            :.....|..|         ||:..:::           ||...||:..:. ........|.|:.:
Human   336 TSGFASTFRE---------DNSSNSLK-----------PGLARGQIKSEP-PSEENEEESITLCL 379

  Fly   429 TQVKSDSKASGTNAALKPGSVTVARSSKSGATASAPPAGSDEESVQYTGLAPLNCSFCGRPLKSV 493
            :..:.|:|.       :.|.|.:.|...|.|.....|||:             .|....|.:.|.
Human   380 SGDEPDAKD-------RAGDVEMDRKQPSPAPTPTAPAGA-------------ACLERSRSVASP 424

  Fly   494 NALRRHIASRHSEIQGKEHECFICMKSFKTKWSLSTHNSRFHREMGCS-----TKGFTKIEYS 551
            :.||               ..|...||.:.....||....|.|...|.     |:|..|.:|:
Human   425 SCLR---------------SLFSITKSVELSGLPSTSQQHFARSPACPFDKGITQGDLKTDYT 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12236	NP_727050.1	BTB	22..116	CDD:279045	22/94 (23%)
		BTB	33..116	CDD:197585	19/83 (23%)
		Herpes_capsid	<376..467	CDD:283714	16/90 (18%)
		C2H2 Zn finger	483..512	CDD:275371	5/28 (18%)
		C2H2 Zn finger	514..535	CDD:275371	5/20 (25%)
BACH2	XP_024302278.1	BTB	113..219	CDD:306997	26/157 (17%)
		bZIP_BACH	726..796	CDD:269867
		coiled coil	730..792	CDD:269867

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	50	1.000	Inparanoid score	I5472
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050