Protein Alignment CG12236 and br

DIOPT Version :10

• Sequence 1: NP_727050.1
• Gene: CG12236 / 31523
• FlyBaseID: FBgn0029822
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001162638.2
• Gene: br / 44505
• FlyBaseID: FBgn0283451
• Length: 1011
• Species: Drosophila melanogaster
• Alignment Length: 799
• Identity: 177/799 - (22%)
• Similarity: 266/799 - (33%)
• Gaps: 298/799 - (37%)

  Fly     1 MATTQQYSLRWNNYLRHLTYSLDNHRLNDDFVDVSLCVDGRRIKAHKVVLSSCSSYFKEIFKENP 65
            |..||.:.||||||...:|.:.:|.|.::.||||:|..:||.||||:||||:||.||:|:.|..|
  Fly     1 MDDTQHFCLRWNNYQSSITSAFENLRDDEAFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTP 65

  Fly    66 HPHPVIIFKFIKFEDLNSIIEFMYQGEVNVQQEALQSFLQTAELLAVQGLTAEEKEKPQIPVAPL 130
            ..||||:.:.:.|.||::::||:|.|||||.|::|||||:|||:|.|.|||.::.|.....:|
  Fly    66 CKHPVILLQDVNFMDLHALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGLTQQQAEDTHSHLA-- 128

  Fly   131 ISEHKLIKTIPSTIRAVNEQQQQVSNVAQA------QTATQTIEIP----------AATLLQATN 179
                                  |:.|:|.:      .|.||::..|          ::||.....
  Fly   129 ----------------------QIQNLANSGGRTPLNTHTQSLPHPHHGSLHDDGGSSTLFSRQG 171

  Fly   180 ASQVPSQVVAA------------------AAAAAAAQQ--------------------------- 199
            |...|...|.:                  ::|||||::
  Fly   172 AGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAAAEETSHAFKRLRGSDNSLPLSGAVGSGSNN 236

  Fly   200 -------LQVQHQQQQHHHVQTTQIQHIQVQSAPPPQQQQQQQQQQQQQQQQQQQQQQQQSQQQQ 257
                   |..:....|......:.|:|....:.||.:::::...................|....
  Fly   237 NSPDLPPLHARSASPQQTPADFSTIKHHNNNNTPPLKEEKRNGPTGNGNSGNGNGNGNGASNGNG 301

  Fly   258 TTPVQTQHLTITNAVALPAASSVKKRKITF---------SDDDDNMYTTE--------------- 298
            .:..........:.:|...|..||...:..         :|:..|..|.|
  Fly   302 ISISDKLGSLTPSPLARAGADDVKSEPMDMVCSNNNANANDEHSNDSTGEHDANRSSSGDGGKGS 366

  Fly   299 ---TVDYAVKD--------EQTIVKTAEMTFLRGAVKMDIP------------------DYIV-- 332
               ..|..:.|        .|.|:..||......|. .:.|                  |..|
  Fly   367 LSSGNDEEIGDGLASHHAAPQFIMSPAENKMFHAAA-FNFPNIDPSALLGLNTQLQQSGDLAVSP 430

  Fly   333 --GEVDDRLS-------DGATPQTS-----QDATTAAAQNVAQYSSEYEIL---------TESEM 374
              |.....||       .|.||..|     .:.:....|.|.|.||.:::|         |.|..
  Fly   431 QGGSTGSLLSGVIVPGGSGGTPSNSSSNNNNNNSNNQQQKVEQQSSPHQLLQQQHHSTPHTNSPQ 495

  Fly   375 EEKYQ-------ADADNAEIAIEMTRLLGTASGTPGAGSGQVMEDSGGGSATTGPS--------- 423
            .::.|       ..:.:..||....|.|..:|        |.|.|:||.|||..|:
  Fly   496 LKQEQPKSGGGSCKSSDLHIAAGSERSLSRSS--------QGMPDAGGHSATPSPTAAYHKRERE 552

  Fly   424 ----------------------------------------------------------------T 424
                                                                            :
  Fly   553 RERERERERERERERSLDHERDLERPGGTGSPPPPPPSHHSHFGQHPLSLLPSHHQLHATHHELS 617

  Fly   425 TVSVTQVKSDSKASGTNAALKPGSVTV---------ARSSKSGATASAP--------------PA 466
            ..:.....:.:.|:..:|..:.||...         |..|.|||.:||.              |.
  Fly   618 AAAAHHAHAHAHAAHAHALARAGSPMEHHHLLHHRRASLSPSGAVSSASGAGGRGGGAGGPGGPG 682

  Fly   467 GSDEESVQYTGLA---------PLN----CSFCGRPLKSVNALRRHIASRHSEIQGKEHE-CFIC 517
            ||...||:...:|         |||    |..||:.|.:...|:||...:|  :|...:. |.:|
  Fly   683 GSLLSSVRAQDVAQANRLLLPLPLNACHRCDVCGKLLSTKLTLKRHKEQQH--LQPLNNAVCNLC 745

  Fly   518 MKSFKTKWSLSTHNSRFHR 536
            .|.|:|..||:.|.|.:||
  Fly   746 HKVFRTLNSLNNHKSIYHR 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12236	NP_727050.1	BTB_POZ_BAB-like	31..114	CDD:349624	48/82 (59%)
		C2H2 Zn finger	483..512	CDD:275371	9/28 (32%)
		C2H2 Zn finger	514..535	CDD:275371	9/20 (45%)
br	NP_001162638.2	BTB_POZ_BAB-like	31..114	CDD:349624	48/82 (59%)
		C2H2 Zn finger	712..729	CDD:275368	6/16 (38%)
		C2H2 Zn finger	742..763	CDD:275368	9/20 (45%)