DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12236 and CG34376

DIOPT Version :9

Sequence 1:	NP_727050.1	Gene:	CG12236 / 31523	FlyBaseID:	FBgn0029822	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_732741.1	Gene:	CG34376 / 42638	FlyBaseID:	FBgn0085405	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	112/531 - (21%)
Similarity:	184/531 - (34%)	Gaps:	188/531 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QYSLRWNNYLRHLTYSLDNHRLNDDFVDVSLCVDGRRIKAHKVVLSSCSSYFKEIFKENPHPHPV 70
            ::.|.|.|:..::.....|.....|.|||:|..||:.:.|||:||:.||.||:|||..||..||:
  Fly     4 EFKLCWKNFQDNIASGFQNLYDRGDLVDVTLACDGKLLHAHKIVLAICSPYFQEIFTTNPCKHPI 68

  Fly    71 IIFKFIKFEDLNSIIEFMYQGEVNVQQEALQSFLQTAELLAVQGLTAEEKEKPQIPVAPLISEHK 135
            ||.|.:.|..:..::||||||.|||:...||||::..:||.::||
  Fly    69 IILKDVSFNIMMELLEFMYQGVVNVKHTELQSFMKIGQLLQIKGL-------------------- 113

  Fly   136 LIKTIPSTIRAVNEQQQQVSNVAQAQTATQTIEIPAATLLQATNASQVPSQVVAAAAAAAAAQQL 200
                      |.|......|:|::                  .::||.|::
  Fly   114 ----------ATNSNSSPGSSVSE------------------KSSSQPPAE-------------- 136

  Fly   201 QVQHQQQQHHHVQTTQIQHIQVQSAPPPQQQQQQQQQQQQQQQQQQQQQQQQSQQQQTTP----- 260
            :..:....:||..:|                   ......:.:....:.:.||..:.|:|
  Fly   137 ESSNTNSTNHHNSST-------------------NSNNNSKSETDHNESKGQSNSRTTSPGGASR 182

  Fly   261 --VQTQHLTITNAVALPAASSVKKRKITFSDDDDNMYTTETVDYAVKDEQTIVKTAEMTFLRGAV 323
              ....||..:|...:|:         .|..|..::|:.:.:..::||..
  Fly   183 ASNDASHLYTSNKRPMPS---------DFGSDSLSIYSGKQLRRSLKDHG--------------- 223

  Fly   324 KMDIPDYIVGEVDDRLSDGATPQTSQDATTAAAQNVAQYSSEYEI--LTESEM-EEKY-----QA 380
                            |.|:.......|.|||..:.:..|.|:.:  :.:..| |::|     :.
  Fly   224 ----------------SGGSEGGGGDHADTAAGLDNSMNSEEFFLPPIPQITMGEQRYDLGGLKR 272

  Fly   381 DADNAEIAIEMTRLLGTASGTPGAGSGQVMEDSGG-GSATTGPSTTVSVTQV------------- 431
            ::|            |...|...||.|    :||. ||.|:..|.:..:...
  Fly   273 ESD------------GHHHGPLSAGGG----NSGSVGSLTSSASPSAPIRNPFAPNFMDSFNYYK 321

  Fly   432 --KSDSKASGTNAALKPGSVTVARS-------------------SKSGAT-ASAPPAGSDEESVQ 474
              .|...:..:|.::.||.|....|                   |||.|. ...|.:||:...:.
  Fly   322 GGNSSGPSGSSNNSVGPGGVNNNGSVGLGSGAEYPNELYMPNDYSKSFANHMDIPSSGSNMVMLS 386

  Fly   475 YTGLAPLNCSF 485
            .|.|...||.|
  Fly   387 TTSLLHGNCVF 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12236	NP_727050.1	BTB	22..116	CDD:279045	44/93 (47%)
		BTB	33..116	CDD:197585	41/82 (50%)
		Herpes_capsid	<376..467	CDD:283714	24/131 (18%)
		C2H2 Zn finger	483..512	CDD:275371	2/3 (67%)
		C2H2 Zn finger	514..535	CDD:275371
CG34376	NP_732741.1	BTB	20..113	CDD:279045	43/92 (47%)
		BTB	31..115	CDD:197585	42/113 (37%)
		FLYWCH	390..443	CDD:282369	4/8 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9606
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020