DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12236 and Aef1

DIOPT Version :9

Sequence 1:	NP_727050.1	Gene:	CG12236 / 31523	FlyBaseID:	FBgn0029822	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001262157.1	Gene:	Aef1 / 40370	FlyBaseID:	FBgn0005694	Length:	454	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	84/385 - (21%)
Similarity:	118/385 - (30%)	Gaps:	153/385 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 AAAAA---------AAAAQQLQVQHQQQQHHHVQTTQIQHIQVQSAPPPQQQQQQQQQQQQQQQQ 244
            |||.|         .||..|..:.:........|.|...|:..       .|||||||||||||.
  Fly    12 AAATAMSSNCDIVIVAAQPQTTIANNNNNETVTQATHPAHMAA-------VQQQQQQQQQQQQQH 69

  Fly   245 QQQQQQQQSQQQQTTPVQTQ-------HL--------TITNAVALPAASSVKKRKITFSDDDDNM 294
            .||||||.|......|..|:       ||        :...|.|:.||.:...:..
  Fly    70 HQQQQQQSSGPPSVPPPPTELPLPFQMHLSGISAEAHSAAQAAAMAAAQAAAAQAA--------- 125

  Fly   295 YTTETVDYAVKDEQTIVKTAEMTFLRGAVKMDIPDYIVGEVDDRLSDGATPQTSQDATTAAAQN- 358
                    |.:.:|....|:.:|.|                           |:...||..:::
  Fly   126 --------AAEQQQPPPPTSHLTHL---------------------------TTHSPTTIHSEHY 155

  Fly   359 VAQYSSEYEILTESEMEEKYQADADNAEIAIEMTRLLGTASGTPGAGSGQVMEDSGGGSATTGP- 422
            :|...||:                                   ||.|:..|    |.|.|...|
  Fly   156 LANGHSEH-----------------------------------PGEGNAAV----GVGGAVREPE 181

  Fly   423 ---------------STTVSVTQVKSDSKASGTNAALKP--GSVTVARSSKSGATASAPPAGSDE 470
                           ||..:..::.:..|....|...|.  .|.|:....|.
  Fly   182 KPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKI------------- 233

  Fly   471 ESVQYTGLAPLNCSFCGRPLKSVNALRRHIASRHSEIQGKEHECFICMKSFKTKWSLSTH 530
                :||..|.||:||.:..:.::.|..|:.....|   |..||.||.|.|:...:|:.|
  Fly   234 ----HTGEKPYNCNFCPKHFRQLSTLANHVKIHTGE---KPFECVICKKQFRQSSTLNNH 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12236	NP_727050.1	BTB	22..116	CDD:279045
		BTB	33..116	CDD:197585
		Herpes_capsid	<376..467	CDD:283714	16/108 (15%)
		C2H2 Zn finger	483..512	CDD:275371	7/28 (25%)
		C2H2 Zn finger	514..535	CDD:275371	7/17 (41%)
Aef1	NP_001262157.1	C2H2 Zn finger	186..206	CDD:275368	2/19 (11%)
		zf-H2C2_2	199..223	CDD:290200	3/23 (13%)
		C2H2 Zn finger	214..234	CDD:275368	5/36 (14%)
		zf-H2C2_2	227..251	CDD:290200	8/40 (20%)
		C2H2 Zn finger	242..262	CDD:275368	5/19 (26%)
		zf-H2C2_2	255..279	CDD:290200	10/26 (38%)
		C2H2 Zn finger	270..290	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050