DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12236 and sna

DIOPT Version :9

Sequence 1:	NP_727050.1	Gene:	CG12236 / 31523	FlyBaseID:	FBgn0029822	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	70/347 - (20%)
Similarity:	112/347 - (32%)	Gaps:	128/347 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 VKKRKITFSDD------------DDNMYTTETVDYAVK---DEQT---------------IVKTA 314
            :|||.|.|.::            |......:..|.::|   ||:|               :.||.
  Fly    10 LKKRPIVFVEERLPQTEALALTKDSQFAQDQPQDLSLKRGRDEETQDYQQPEPKRDYVLNLSKTP 74

  Fly   315 EMTFLRG------AVKMDIPDYIVGEVDDR-LSDGATPQTSQDATT----------AAAQN---- 358
            |......      :..::..||:..|:..| |:.|.|..|:...||          ||..|
  Fly    75 ERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAGCNPISA 139

  Fly   359 --------VAQYSSEYEILTESEMEEKYQADADNAEIAIEMTRLLGTASGTPGAG--SGQVMEDS 413
                    :|.:.|....:...:....||          :|     |...:||:.  :|...||.
  Fly   140 LWSSYQPHLAAFPSPASSMASPQSVYSYQ----------QM-----TPPSSPGSDLETGSEPEDL 189

  Fly   414 GGGSATTGPSTTVSVTQVKSDSKASGTNAALKPG-SVTVARSSKSGATAS--------------- 462
            ...:....|:......:.||.|  ||.:.:...| |.|.|.|:.|.:.|:
  Fly   190 SVRNDIPLPALFHLFDEAKSSS--SGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQK 252

  Fly   463 ---------------APPAGSDEESVQYTGLAPLNCSFCGRPLKSVNALRRHIASRHSEIQGKEH 512
                           .|.|..::|...:      :|..||:...::.||:.||         :.|
  Fly   253 MYSTSMGLSKHRQFHCPAAECNQEKKTH------SCEECGKLYTTIGALKMHI---------RTH 302

  Fly   513 ----ECFICMKSFKTKWSLSTH 530
                :|.||.|:|...|.|..|
  Fly   303 TLPCKCPICGKAFSRPWLLQGH 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12236	NP_727050.1	BTB	22..116	CDD:279045
		BTB	33..116	CDD:197585
		Herpes_capsid	<376..467	CDD:283714	23/123 (19%)
		C2H2 Zn finger	483..512	CDD:275371	7/28 (25%)
		C2H2 Zn finger	514..535	CDD:275371	8/17 (47%)
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	8/17 (47%)
		zf-H2C2_2	321..344	CDD:290200	2/4 (50%)
		zf-C2H2	334..356	CDD:278523
		C2H2 Zn finger	336..356	CDD:275368
		zf-H2C2_2	348..373	CDD:290200
		C2H2 Zn finger	364..380	CDD:275368
		C2H2 Zn finger	247..267	CDD:275368	0/19 (0%)
		C2H2 Zn finger	282..302	CDD:275368	7/28 (25%)
		zf-C2H2	306..328	CDD:278523	8/19 (42%)
		COG5048	307..>356	CDD:227381	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050