DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12236 and Zbtb14

DIOPT Version :10

Sequence 1:NP_727050.1 Gene:CG12236 / 31523 FlyBaseID:FBgn0029822 Length:553 Species:Drosophila melanogaster
Sequence 2:NP_033573.1 Gene:Zbtb14 / 22666 MGIID:1195345 Length:449 Species:Mus musculus


Alignment Length:533 Identity:106/533 - (19%)
Similarity:185/533 - (34%) Gaps:163/533 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 SLDNHRLNDDFVDVSLCVDGRRIKAHKVVLSSCSSYFKEIFKE-NPHPHPVIIFKFIKFEDLNSI 84
            :|:..||..:|.|:::.|:..:.:||:.||::||:|||::||: ......||...|::.:....:
Mouse    25 TLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEVDSSSVIEIDFLRSDIFEEV 89

  Fly    85 IEFMYQGEVNVQQEALQSFLQTAELLAVQGLTAEEKEKPQIPVAPLISEHKLIKTIPSTIRAVNE 149
            :.:||..:::|::|.:...:.:.::|.::.|                  .||.           .
Mouse    90 LNYMYTAKISVKKEDVNLMMSSGQILGIRFL------------------DKLC-----------S 125

  Fly   150 QQQQVSNVAQAQTATQTIEIPAATLLQATNASQVPSQVVAAAAAAAAAQQLQVQHQQQQHHHVQT 214
            |::.||:..::               ...:.|:...::......||.||...|:....|......
Mouse   126 QKRDVSSPDES---------------NGQSKSKYCLKLNRPIGDAADAQDDDVEEIGDQDDSPSD 175

  Fly   215 TQIQHIQVQSAPPPQQQQQQQQQQQQQQQQQQQQQQQQSQQQQTTPVQTQHLTITNAVALPAASS 279
            .     .|:..||                         ||:...:|..|  |.:..|: |....|
Mouse   176 D-----TVEGTPP-------------------------SQEDGKSPTTT--LRVQEAI-LKELGS 207

  Fly   280 VKKRKIT-FSDDDDNMYTTETVDYAVKDEQTIVKTAEMTFLRGAVKMDIPDYIVGEVDDRLSDGA 343
            .:.||:. :..:.::|.|.|:.|...:..|.      :||..|          :.||.|..:.| 
Mouse   208 EEVRKVNCYGQEVESMETPESKDLGSQTPQA------LTFNDG----------MSEVKDEQTPG- 255

  Fly   344 TPQTSQDATTAAAQNVAQYSSEYEILTESEMEEKYQADADNAEIAIEMTRLLGTASGTPGAGSGQ 408
                   .||||:      ..::|.|......|:....|                       .|:
Mouse   256 -------WTTAAS------DMKFEYLLYGHHREQIACQA-----------------------CGK 284

  Fly   409 VMEDSGGGSATTGPSTTVSVTQVKSDSKASGTNAALKPGSVTVARSSKSGATASAPPAGSDEESV 473
            ...|.|               :::...|   .:.|.:|   .|......|.|..   |...|...
Mouse   285 TFSDEG---------------RLRKHEK---LHTADRP---FVCEMCTKGFTTQ---AHLKEHLK 325

  Fly   474 QYTGLAPLNCSFCGRPLKSVNALRRHIASRHSEIQGKEHECFICMKSFKTKWSLSTHNSRFHRE- 537
            .:||..|.:|..||:.......|::|.....:|   :...|.:|.|:||.|..|..|..|...| 
Mouse   326 IHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNE---RPFACHMCDKAFKHKSHLKDHERRHRGEK 387

  Fly   538 ---MGCSTKGFTK 547
               .|..||.|.|
Mouse   388 PFVCGSCTKAFAK 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12236NP_727050.1 BTB_POZ_BAB-like 31..114 CDD:349624 22/83 (27%)
C2H2 Zn finger 483..512 CDD:275371 6/28 (21%)
C2H2 Zn finger 514..535 CDD:275371 9/20 (45%)
Zbtb14NP_033573.1 BTB_POZ_ZBTB14 18..131 CDD:349513 29/134 (22%)
Nuclear localization signal. /evidence=ECO:0000255 50..66 8/15 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 156..194 11/67 (16%)
C2H2 Zn finger 279..299 CDD:275368 5/60 (8%)
SFP1 <303..383 CDD:227516 23/88 (26%)
C2H2 Zn finger 307..327 CDD:275368 4/22 (18%)
zf-H2C2_2 319..344 CDD:463886 7/24 (29%)
C2H2 Zn finger 335..355 CDD:275368 5/19 (26%)
C2H2 Zn finger 363..383 CDD:275368 8/19 (42%)
C2H2 Zn finger 391..407 CDD:275368 5/10 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 405..424
Blue background indicates that the domain is not in the aligned region.

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