Protein Alignment CG12236 and NACC1

DIOPT Version :10

• Sequence 1: NP_727050.1
• Gene: CG12236 / 31523
• FlyBaseID: FBgn0029822
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_443108.1
• Gene: NACC1 / 112939
• HGNCID: 20967
• Length: 527
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 68/242 - (28%)
• Similarity: 101/242 - (41%)
• Gaps: 50/242 - (20%)

  Fly     1 MATTQQYSLRWNNYLRHLTYSLDNHRLNDDFVDVSLCVDGRRIKAHKVVLSSCSSYFKEIFKENP 65
            ||.|.|..:  .|:...:...|:..||...:.|||:.|.|...|||:.||::.||||:::| .|.
Human     1 MAQTLQMEI--PNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLF-NNS 62

  Fly    66 HPHPVIIFKFIKFEDLNSIIEFMYQG--EVNVQQEAL----QSFLQTAELLA------------- 111
            ....|.:...::.:....|:.|.|.|  .:||..:.|    ..|||..|::.
Human    63 RSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPS 127

  Fly   112 --VQGLTAEE--KEKPQIPVA------------PLIS-------EHKLIKTIPSTIRAVNEQQQQ 153
              .|||.|||  ..:||.|||            ||:|       |...::.:|...|..:..|::
Human   128 CDSQGLHAEEAPSSEPQSPVAQTSGWPACSTPLPLVSRVKTEQQESDSVQCMPVAKRLWDSGQKE 192

  Fly   154 V---SNVAQAQTATQTIEIPAATLLQATNASQVPSQVVAAAAAAAAA 197
            .   .|.::......|.::.|....|.....|.|  |||||..|.||
Human   193 AGGGGNGSRKMAKFSTPDLAANRPHQPPPPQQAP--VVAAAQPAVAA 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12236	NP_727050.1	BTB_POZ_BAB-like	31..114	CDD:349624	28/103 (27%)
		C2H2 Zn finger	483..512	CDD:275371
		C2H2 Zn finger	514..535	CDD:275371
NACC1	NP_443108.1	BTB_POZ_BTBD14B_NAC1	3..125	CDD:349599	34/124 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..153		11/21 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..292		12/30 (40%)
		BEN	396..474	CDD:214981