DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12236 and Btbd18

DIOPT Version :9

Sequence 1:	NP_727050.1	Gene:	CG12236 / 31523	FlyBaseID:	FBgn0029822	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	XP_002729248.1	Gene:	Btbd18 / 100363270	RGDID:	2323370	Length:	724	Species:	Rattus norvegicus

Alignment Length:	524	Identity:	104/524 - (19%)
Similarity:	183/524 - (34%)	Gaps:	120/524 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YLRHLTYSLDNHRLNDDFVDVSLCVDGRRIKAHKVVLSSCSSYFKE-IFKENPHPHPVIIFKF-- 75
            :||.....|.:.:.:..|.|..|..:|..:.||..:||:||.:|.| :.:|.|.....::.:.
  Rat    16 FLRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLELGG 80

  Fly    76 IKFEDLNSIIEFMYQGEVNVQQEALQSFLQTAELLAVQGLTAEE----------------KEKPQ 124
            :|.:.|..:::|:|..|:.|.||..|..|..|..|.|..|...:                :|..|
  Rat    81 LKIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNRECLQ 145

  Fly   125 IPVAPLISEHKL-----------IKTIPSTIRAV-------NEQQQQVSNVAQAQTATQTIEI-- 169
            .|.|..||...:           :...||.:.||       .|...:.||:..|...:.|:.:
  Rat   146 PPSAAPISARVVVPRSRPRTPLPVTQTPSPLGAVKLKSLGEEEGAHKKSNLPNADNLSDTLLLKK 210

  Fly   170 -PAATLLQATNAS------------QVPSQVVAAAAAAAAAQQLQVQ----HQQQQHHHVQTTQI 217
             ....|.|..::|            ..|......:...:..:||..:    .:.:...||.|::.
  Rat   211 KARVCLTQERSSSPSSQREGPKENKSNPGSTALPSLYPSVDEQLLPRKIRLSRSKPSPHVYTSKP 275

  Fly   218 QHIQVQSAP------PPQQQQQQQQQQQQQQQQQQQQQQQQSQQQQT-------------TPVQT 263
            .  .:.|.|      |.::..:|:...:..|...:|:..:.|..|.|             .|...
  Rat   276 S--SMLSGPSSMPTAPGRRLWRQRTVSEATQGVDKQKPGEVSTLQSTPDPPDVGKTGGKKQPSPE 338

  Fly   264 QHLTITNAVALPAASSVKKRKITFSDDDDNMYTTETVDYA----VKDEQTIVKTAEM-----TFL 319
            .....:|:|.......||.|||.      |....|.|...    .:|...|:::::.     |.|
  Rat   339 SRAPASNSVEEGQVGRVKLRKIV------NGTCWEVVQEPPIRNTQDSPQILESSDADEPPGTLL 397

  Fly   320 RGAVKMDIPDYIV----GEVDDRLSD------------------GATPQTSQDATTAAAQNVAQY 362
            ....:.:||..|.    ...:.||.|                  |::|..:.............|
  Rat   398 SSVNEQEIPARIQLCHDSPENSRLQDILLSASHSPDHPVVKSEFGSSPMLTGKEPELNIDCREPY 462

  Fly   363 SSEYEILTESEMEEKYQ--ADADNAEIAIEMTRLLGTASGTPGAGSGQVMEDSGGGSATTGPSTT 425
            :.:..:|::....|:|:  :.|..:|:...:..:|..:...|..||   :|..|.....| ||..
  Rat   463 TFDTTLLSQPCEAEQYRITSAAATSELEEILDFMLCGSDVEPPVGS---LESPGAEGCRT-PSYH 523

  Fly   426 VSVT 429
            :|.|
  Rat   524 LSET 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12236	NP_727050.1	BTB	22..116	CDD:279045	28/96 (29%)
		BTB	33..116	CDD:197585	26/85 (31%)
		Herpes_capsid	<376..467	CDD:283714	15/56 (27%)
		C2H2 Zn finger	483..512	CDD:275371
		C2H2 Zn finger	514..535	CDD:275371
Btbd18	XP_002729248.1	BTB	24..123	CDD:279045	29/98 (30%)
Btbd18	XP_002729248.1	BTB	35..123	CDD:197585	27/87 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910