Protein Alignment CG4020 and FAR2

DIOPT Version :10

• Sequence 1: NP_572276.1
• Gene: CG4020 / 31522
• FlyBaseID: FBgn0029821
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 176/504 - (34%)
• Similarity: 264/504 - (52%)
• Gaps: 37/504 - (7%)

  Fly     2 TIPEAFEDQEIFVTGASGFVGKALIEKLLRSCPKLGRIYVLMRPKKGHTIEERLQLQWESRLYER 66
            ||...:..:.|.:|||:||:||.|:|||.|:.|.|..||:|:|||.|.|:::|:....:|:|:|:
Human    23 TIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEK 87

  Fly    67 LRREQPNARSKLVAIAGDVEQLGLGIGSADLERLRN-VNIVYHSAASVRFDDALSTAILLNTRGT 130
            ::...||...|:.||..|:.|....|...|::.|.: .||::|.||:|||||.|..|:.||...|
Human    88 VKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTAT 152

  Fly   131 HELVKLALEWPKLKAFVHVSTTYSNPGVLEVEERVYPPLADWRTTIKLAETYDAEILDIFNLKYG 195
            .:|:.:|.:.|||:||:|:||.|||..:..::|.:||...:.:..|...|..|..|:|....|..
Human   153 RQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPKLI 217

  Fly   196 NFQPNTYTFTKSLAEQVVNEYRDRLPIFIFRPSIVVSTIEEPVPGWADNFNGPTGLLVACGVGIL 260
            ...||.||:||:|.|.||.:....|.|.|.|||||.:|.:||.|||.||.|||.|:::|.|.|.|
Human   218 RDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKGFL 282

  Fly   261 RSQNCDPNIVADFVPADIVARTLI-----TSVYKFMGESKSRAKDSDLYVVNCATANISPIT--- 317
            |:....|..|||.:|.|.|...::     |:|:        |.|.:.:|  :..:.|::|..
Human   283 RAIKATPMAVADVIPVDTVVNLMLAVGWYTAVH--------RPKSTLVY--HITSGNMNPCNWHK 337

  Fly   318 MGEVIDIGKTFIRKNPFEKTLWLPGGGMTTCPVLHFVRFCTMHLLMAIVVDTLLRLYNEKPFLMK 382
            ||  :.:..|| .|.|||:....|....|:............|...||:.|..|||...||.:.|
Human   338 MG--VQVLATF-EKIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTK 399

  Fly   383 LQRRIFAAFSALQVFAMTEWHFQNDNFRAL-HDVVPANE-VSNFGFMQHANINYTEFFQHGIRGA 445
            |..|:....|.|:.|....|.:...|...| .::.|.:: |.||...|   :|:.|:.::.:.|.
Human   400 LMNRLLRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQ---LNWLEYIENYVLGV 461

  Fly   446 KEFLLKESPESSSAARFRVKIFYVLDFLCRGIVYSF---LLRLIFRFLV 491
            |::||||.......|:.|:|       ..|.|.|.|   |..:.:|.|:
Human   462 KKYLLKEDMAGIPKAKQRLK-------RLRNIHYLFNTALFLIAWRLLI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4020	NP_572276.1	FAR-N_SDR_e	12..333	CDD:187547	128/329 (39%)
		Sterile	359..451	CDD:460779	28/93 (30%)
FAR2	XP_011519049.1	FAR-N_SDR_e	31..335	CDD:187547	123/313 (39%)
		Sterile	377..467	CDD:460779	28/92 (30%)