DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4020 and CG17562

DIOPT Version :9

Sequence 1:	NP_001259264.1	Gene:	CG4020 / 31522	FlyBaseID:	FBgn0029821	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_650566.1	Gene:	CG17562 / 42021	FlyBaseID:	FBgn0038449	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	171/505 - (33%)
Similarity:	262/505 - (51%)	Gaps:	30/505 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IPEAFEDQEIFVTGASGFVGKALIEKLLRSCPKLGRIYVLMRPKKGHTIEERLQLQW-ESRLYER 66
            |...|..:.:|:|||:||:||.:||||||: .::.|||||:|||:|..|::|: :.| :..::|.
  Fly     5 IQRCFRSKTVFLTGATGFLGKVVIEKLLRT-TEVKRIYVLIRPKRGVEIKDRI-ITWSKDAVFEL 67

  Fly    67 LRREQPNARSKLVAIAGDVEQLGLGIGSADLERLRN-VNIVYHSAASVRFDDALSTAILLNTRGT 130
            |.:.:|.|..::..||||.....|||...|...|.: |.||.|.||:|||::.|..|:.:|||.|
  Fly    68 LLKSKPEALQRVCPIAGDCLDFDLGISENDRRLLASEVQIVIHGAATVRFNEPLHVALAINTRAT 132

  Fly   131 HELVKLALEWPKLKAFVHVSTTYSNPGVLEVEERVYPPLADWRT--TIKLAETYDAEILDIFNLK 193
            ..:::||.|..:|:|||||||.:||..:..::|..||...:..:  .:.:||....|:||  |::
  Fly   133 KLMIQLAKEMRQLEAFVHVSTAFSNCVIYNIKENFYPEHLNCSSDKVLAMAELMSDELLD--NME 195

  Fly   194 ---YGNFQPNTYTFTKSLAEQVVNEYRDRLPIFIFRPSIVVSTIEEPVPGWADNFNGPTGLLVAC 255
               .|:| |||||:||:|||.|:.:....||:.||||:::::..:||:.||.||..||..:|...
  Fly   196 QALLGSF-PNTYTYTKALAEDVILKEAGGLPLCIFRPAVIIAAHKEPISGWIDNMYGPMAILFGV 259

  Fly   256 GVGILRSQNCDPNIVADFVPADIVARTLITSVYKFMGESKSRAKDSDLYVVNCATANISPITMGE 320
            ..|:||....|.:..|..||.|..|...:...:|.:.|...........:...|....:.||.||
  Fly   260 ARGVLRIATIDHHAEASLVPVDYCANLTLACTWKTIVEGNEMGTQETPLIYQLAPIEQNKITHGE 324

  Fly   321 VI----DIGKTFIRKNPFEKTLWLPGGGMTTCPVLHFVRFCTMHLLMAIVVDTLLRLYNEKPFLM 381
            .|    | |:|   ..|..|.:|.|.....|.|.|..:.....|.|.|...|..|.|...||.|:
  Fly   325 FIRHALD-GRT---NCPLTKMIWYPFIHCITVPWLFPLAAFFYHTLPAYFFDLALWLSGRKPRLV 385

  Fly   382 KLQRRIFAAFSALQVFAMTEWHFQNDNFRALHDVVPANEVSNFGFMQHANINYTEFFQHGIRGAK 446
            |:.::|......|..||...|.|...|...|...: :.|.....:....::|:.|:|...:||.:
  Fly   386 KVYQKIHKTLGILGPFACKSWRFDMRNTDHLRQQM-SEEDRRIYYFDMVSLNWKEYFVQALRGMR 449

  Fly   447 EFLLKESPESSSAARFR--VKIFYVLDFLCRGIVYSFLLRLIFRFLVRLW 494
            :||..|:|...|.|:.:  :|...:|..:.:|:       |.|..|:.||
  Fly   450 QFLGNEAPTPESIAQGKKLIKRLKLLHHILQGV-------LCFVALLALW 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4020	NP_001259264.1	FAR-N_SDR_e	12..333	CDD:187547	124/331 (37%)
CG4020	NP_001259264.1	FAR_C	359..450	CDD:176924	25/90 (28%)
CG17562	NP_650566.1	PLN02996	10..442	CDD:215538	152/441 (34%)
		FAR-N_SDR_e	12..329	CDD:187547	121/321 (38%)
		FAR_C	362..452	CDD:176924	24/90 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466784
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.900