DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4020 and far1

DIOPT Version :9

Sequence 1:	NP_001259264.1	Gene:	CG4020 / 31522	FlyBaseID:	FBgn0029821	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	513	Identity:	185/513 - (36%)
Similarity:	279/513 - (54%)	Gaps:	30/513 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTIPEAFEDQEIFVTGASGFVGKALIEKLLRSCPKLGRIYVLMRPKKGHTIEERLQLQWESRLYE 65
            :||||.:..:.:.:|||:||:||.|:||||||||.:...|||:|||.|...:.|:......:|::
Zfish     2 VTIPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFD 66

  Fly    66 RLRREQPNARSKLVAIAGDVEQLGLGIGSADLERLRN-VNIVYHSAASVRFDDALSTAILLNTRG 129
            |||.:||:...|:|||..|:.|..|.:.:.|.|.|.. :|:|:|.||::||::.|..|:.||...
Zfish    67 RLREDQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLA 131

  Fly   130 THELVKLALEWPKLKAFVHVSTTYSNPGVLEVEERVYPPLADWRTTIKLAETYDAEILDIFNLKY 194
            |.::|.||.....|:.|:||||.|:|.....:||.||||..|:|..|...|..|.:::.:...:.
Zfish   132 TQKMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYRKLIDTLEWMDDKLVSLMTPRL 196

  Fly   195 GNFQPNTYTFTKSLAEQVVNEYRDRLPIFIFRPSIVVSTIEEPVPGWADNFNGPTGLLVACGVGI 259
            ...:|||||:||:||||:|.:....|.|.|.|||||.::.:||.|||.||||||:|:.:|.|.||
Zfish   197 LGERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGI 261

  Fly   260 LRSQNCDPNIVADFVPADIVARTLITSVYKFMGESKSRAKDSDLYVVNCATANISPITMGEV-ID 323
            ||:.....|.|||.||.|:|..|.:.:.: :.| |:..|:...|.|.||.|..|:|...||| ..
Zfish   262 LRTMRASNNAVADLVPVDVVINTTLAAAW-YSG-SQRHARPRSLLVYNCTTGGINPFHWGEVEYH 324

  Fly   324 IGKTFIRKNPFEKTLWLPGGGMTTCPVLHFVRFCTMHLLMAIVVDTLLRLYNEKPFLMKLQRRIF 388
            :..|| ::||.|:....|...:||..:::.......|...|.:.|..||:...:|.:||...|:.
Zfish   325 VISTF-KRNPLEQAFRRPNVNLTTNHLINQYWIAVSHKAPAFLYDLFLRMSGREPRMMKTITRLH 388

  Fly   389 AAFSALQVFAMTEWHFQNDNFRALHDVVPANE--VSNFGFMQHANINYTEFFQHGIRGAKEFLLK 451
            .|...|:.|....|.:..||...|.:.:.|.:  |.||...|   :::.|:.::...|.|:::|.
Zfish   389 KAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQ---LHWAEYMENYCMGTKKYVLN 450

  Fly   452 ESPESSSAARFRV-------------------KIFYVLDFLCRGIVYSFLLRLIFRFL 490
            |......|||..:                   :||.....:.|.|.| |::.|.|:||
Zfish   451 EELSGLPAARKHLNKLRNIRYTFNTVLVVLIWRIFIARSQMARNIWY-FVVSLCFKFL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4020	NP_001259264.1	FAR-N_SDR_e	12..333	CDD:187547	136/322 (42%)
CG4020	NP_001259264.1	FAR_C	359..450	CDD:176924	24/92 (26%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	136/324 (42%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	24/92 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593278
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950