Protein Alignment Act5C and ACTL8

DIOPT Version :10

• Sequence 1: NP_511052.1
• Gene: Act5C / 31521
• FlyBaseID: FBgn0000042
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_110439.2
• Gene: ACTL8 / 81569
• HGNCID: 24018
• Length: 366
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 124/375 - (33%)
• Similarity: 192/375 - (51%)
• Gaps: 36/375 - (9%)

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVG--------RPRHQGVMVGMG----QKDSYVGDEAQS 61
            :::|:|||..|||.||.:.|:.|||:||.        .|.:....|.:|    ..|
Human     6 VIIDHGSGFLKAGTAGWNEPQMVFPNIVNYLPCKENPGPSYARRRVSLGIDICHPD--------- 61

  Fly    62 KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFE 126
                 |..||||.|.:.||:.::.:|.....|..| ..|..||::||.||...|:|:||.:|:||
Human    62 -----TFSYPIERGRILNWEGVQYLWSFVLENHRR-EQEVPPVIITETPLREPADRKKMLEILFE 120

  Fly   127 TFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLM 191
            ..:.|::.:|.|..:||||||..||:|:|||.|::...|.::|..||.:...|:.||:||:.||:
Human   121 LLHVPSVLLADQLQMSLYASGLLTGVVVDSGYGLTRVQPFHQGRPLPASGKTLEFAGQDLSAYLL 185

  Fly   192 KILTERGYSFTTTAEREIVRDIKEKLCYV------ALDFEQEMATAASSSSLEKSYELPDGQVIT 250
            |.|.:.........:.|.|...:...|||      ||||.:...:|...|:   :|:||||..:.
Human   186 KSLFKEDCDRRCLFQLETVAVTQMNKCYVPQNLGEALDFRERQQSALDESN---TYQLPDGSRVE 247

  Fly   251 IGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQ 315
            :...:...||..|.|.........|......|:..|::.:|..|.::.:..||.|:|||...|:.
Human   248 LTPMQRVAPEMFFSPQVFEQPGPSIPRAIVESVESCEISLRPLLVSHVMACGGNTLYPGFTKRLF 312

  Fly   316 KEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDE 365
            :|:.....|:.|..:.....|.:|||:|.|::|.|||:|..|:|::||.|
Human   313 RELMGDHVSSTKATVWEGSNRNFSVWLGASVVAHLSTYQSEWMSREEYGE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act5C	NP_511052.1	ASKHA_NBD_actin	7..371	CDD:466823	124/375 (33%)
ACTL8	NP_110439.2	ACTIN	4..363	CDD:214592	124/375 (33%)