DRSC/TRiP Functional Genomics Resources

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Protein Alignment Act5C and Actr8

DIOPT Version :9

Sequence 1:NP_001014725.1 Gene:Act5C / 31521 FlyBaseID:FBgn0000042 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_001296388.1 Gene:Actr8 / 361107 RGDID:1311878 Length:624 Species:Rattus norvegicus


Alignment Length:475 Identity:80/475 - (16%)
Similarity:164/475 - (34%) Gaps:167/475 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 QKDSYVGDEA-------------QSKRGILTLKYPIEHGIVTN-WDDMEKIWHHTFYNELRVAPE 100
            |.:..||:||             ..:||.|.: :|...|.:|. ..|:|.||.|.....|.:..:
  Rat   162 QPEYLVGEEALYVNPLDCYNIHWPIRRGQLNI-HPGPGGSLTAVLADIEVIWSHAIQKYLEIPLK 225

  Fly   101 E---HPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSH 162
            :   :..:|....:..|.:.:::..::........:.|..::|.:.:.||.::..|:|.||..:.
  Rat   226 DLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLSSTCVVDVGDQKTS 290

  Fly   163 TVPIYEGYALPHAILRLDLA--GRDLTDYLMKILTERGYSFTTTAERE----------IVRDIKE 215
            ...:.:|  :.|...||.||  |.|::.....::...|:.:     ||          :::.:||
  Rat   291 VCCVEDG--VSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPY-----RECQLANKMDCLLLQHLKE 348

  Fly   216 KLCYVALDFEQEMATAASSSSLEKSYEL--PDGQVI----TIGNERFRCPEALFQPSFLGM---- 270
            ..|::..|.         |...:..:::  ||...:    .:|:|:.:.|.|||.|:..|:    
  Rat   349 TFCHLDQDI---------SGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQK 404

  Fly   271 ----------------------------------------------------------------- 270
                                                                             
  Rat   405 MTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQ 469

  Fly   271 -------------------------------------EACGIHETTYNSIMKCDV-DIRKDLYAN 297
                                                 :|.|:.:...:|:..|.. |.:|.:|::
  Rat   470 EVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSS 534

  Fly   298 TVLSGGTTMYPGIADRMQKEITALAPSTMK-----IKIIAPP---ERKYSVWIGGSILASLSTFQ 354
            .::.||..|:....:.:|..|....|.:.:     :.:|..|   :.:...|.||::||.|.|.|
  Rat   535 ILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLISWKGGAVLACLDTTQ 599

  Fly   355 QMWISKQEYDESGPSIVHRK 374
            ::||.::|:...|..::..:
  Rat   600 ELWIYQREWQRFGVRMLRER 619

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Act5CNP_001014725.1 PTZ00281 1..376 CDD:173506 80/475 (17%)
Actr8NP_001296388.1 NBD_sugar-kinase_HSP70_actin 162..619 CDD:418402 80/473 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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