Protein Alignment Act5C and ACTRT1

DIOPT Version :10

• Sequence 1: NP_511052.1
• Gene: Act5C / 31521
• FlyBaseID: FBgn0000042
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_612146.1
• Gene: ACTRT1 / 139741
• HGNCID: 24027
• Length: 376
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 180/372 - (48%)
• Similarity: 255/372 - (68%)
• Gaps: 3/372 - (0%)

  Fly     5 EVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLK 69
            :|.|::.|||||:||||.:|:..||.|..|::|..:....:..:.|| .:||.||..|...|.|.
Human     8 DVPAVIFDNGSGLCKAGLSGEIGPRHVISSVLGHCKFNVPLARLNQK-YFVGQEALYKYEALHLH 71

  Fly    70 YPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMY 134
            ||||.|:||.||||||:|.|.|..||.|.|.:.|||:||..|||:..|||:.::|||||:.|..|
Human    72 YPIERGLVTGWDDMEKLWKHLFERELGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVPGFY 136

  Fly   135 VAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGY 199
            ::..||.:||||...||:|:||||||:.||||:|||:||||:.:|.:||||:|::|.::|...|:
Human   137 LSNHAVAALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLTRLLFASGF 201

  Fly   200 SFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQ 264
            :|.....:.:|.:|||||||:||:.|:|:  ..|...:..:|.||||.||..|:|.::.||.||.
Human   202 NFPCILNKAVVNNIKEKLCYIALEPEKEL--RKSRGEVLGAYRLPDGHVIHFGDELYQVPEVLFA 264

  Fly   265 PSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIK 329
            |..||:.:.|:.:...:||||||.||:..|||:.|||||||:.||:.:|:.||:..||.....||
Human   265 PDQLGIHSPGLSKMVSSSIMKCDTDIQNKLYADIVLSGGTTLLPGLEERLMKEVEQLASKGTPIK 329

  Fly   330 IIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 376
            |.|.|:|.:|.|||.||:.|:|:|:|||::..::.|.|.|:|.|:||
Human   330 ITASPDRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act5C	NP_511052.1	ASKHA_NBD_actin	7..371	CDD:466823	175/363 (48%)
ACTRT1	NP_612146.1	ASKHA_NBD_actin_Arp-T1-3	10..367	CDD:466848	173/359 (48%)