Protein Alignment Act5C and ACTR3

DIOPT Version :9

• Sequence 1: NP_001014725.1
• Gene: Act5C / 31521
• FlyBaseID: FBgn0000042
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005712.1
• Gene: ACTR3 / 10096
• HGNCID: 170
• Length: 418
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 151/415 - (36%)
• Similarity: 215/415 - (51%)
• Gaps: 53/415 - (12%)

  Fly     8 ALVVDNGSGMCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDSYVGDEAQSKRG 64
            |.|||.|:|..|.|:||:..|:.:.||.        ||....:.||.|:...|.::||||..|..
Human     7 ACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEAIEKPT 71

  Fly    65 ILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN 129
            ..| |:||.||||.:||.||:......:..||..||:|..||||.|||...|||...:||||:||
Human    72 YAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFN 135

  Fly   130 TPAMYVAIQAVLSLYAS-------GRT-TGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDL 186
            .|.:|:|:||||:|.||       .|| ||.|:||||||:|.:|:.|||.:...|..:.:||||:
Human   136 VPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDI 200

  Fly   187 TDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSS------------LEK 239
            |.::.::|.:|..........|..:.:||:..||..|..:|.....:..|            .:|
Human   201 TYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKK 265

  Fly   240 SYELPDGQVITIGNERFRCPEALFQPSFLGME-ACGIHETTYNSIMKCDVDIRKDLYANTVLSGG 303
            .:.      |.:|.|||..||..|.|.|...: ...|.|.....|..|.:|:|:.||.|.|||||
Human   266 EFS------IDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGG 324

  Fly   304 TTMYPGIADRMQKEIT----------------ALAPSTMKIKIIAPPERKYSVWIGGSILASLST 352
            :||:.....|:|:::.                .|.|..:.:::|....::|:||.|||:|||...
Human   325 STMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPE 389

  Fly   353 FQQMWISKQEYDESGPSIV-HRKCF 376
            |.|:..:|::|:|.||||. |...|
Human   390 FYQVCHTKKDYEEIGPSICRHNPVF 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act5C	NP_001014725.1	PTZ00281	1..376	CDD:173506	150/413 (36%)
ACTR3	NP_005712.1	PTZ00280	2..417	CDD:240343	151/415 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820