DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16721 and TCP11X1

DIOPT Version :9

Sequence 1:	NP_001284913.1	Gene:	CG16721 / 31520	FlyBaseID:	FBgn0029820	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001355087.1	Gene:	TCP11X1 / 100996631	HGNCID:	48369	Length:	407	Species:	Homo sapiens

Alignment Length:	435	Identity:	112/435 - (25%)
Similarity:	203/435 - (46%)	Gaps:	78/435 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VHKAFWDLLRVQLDRQPPSYDQAIRLLAEIKECFPQLLSPNNERALAHINEVLDDSVIRQQAERG 163
            ::.|||:.|:.||...||.:..|:.||.::||          .|....|.|.||..:::|:||.|
Human     1 MYNAFWNHLKEQLLSTPPDFTCALELLKDVKE----------NRLRNEIEEALDTDLLKQEAEHG 55

  Fly   164 TLDFRAYANFVINILSRSCSPARDEAVAALRKIDDVVDTFRCILELMTLMKLDMANFMLRLARTE 228
            .||....:|:::|:::..|:|.||||:..|..|.|.|...|.||.::.|||:||.|:.::..|..
Human    56 ALDVPHLSNYILNLMALLCAPVRDEAIQKLETIRDPVQLLRGILRVLGLMKMDMVNYTIQSFRPY 120

  Fly   229 IAANSVQYEKEKFSKYLREFHGNVGFPATEDWLQRHR-------------------------SGS 268
            :..:|:|||:.||.:.|.:....:.:  |..||.:..                         ||:
Human   121 LQEHSIQYEQAKFQELLDKQPSLLDY--TTKWLTKAATDITTLCPSSPDSPSSSCSMVCSLPSGA 183

  Fly   269 SDDE-------TIYNAYMQLIDYPADK-EFPELLRIDKERFAGLSWRAQRLILCASLISVAQGM- 324
            .::.       .:|..|:.|:.:..:. ||||.|.:|:.|...|:::..:|.:.||::.||:..
Human   184 GNNSEPPSPTMVLYQGYLNLLLWDLENVEFPETLLMDRIRLQELAFQLHQLTVLASVLLVARSFS 248

  Fly   325 -PIISQRRE--NRIKLAQQLDIIVQDIKNQDQVASTIESCYEQIRSFVNKALEQENLPALSDADQ 386
             .::.:..|  :|:|...:  .:.::..::.:  .|:.|..||:...|::.|:...|..||..:.
Human   249 GEVLFRSPEFVDRLKCTTK--ALTEEFISRPE--ETMLSVSEQVSQEVHQGLKDMGLTTLSSENT 309

  Fly   387 AALKNQVLKLANKTSPVPSLMAKRLDGYVRVTLR------SNGSIPPPPSGFADYQEELVAFIAS 445
            |:|..|:..:..|.:.:.|:    :|.::|..|:      ...|:...|.|....::||......
Human   310 ASLLGQLQNITKKENCIRSI----VDQWIRFFLKCCLLHGMQESLLHFPGGLILIEKELAELGWK 370

  Fly   446 FRRLVSYNHAVFGEHFHQILNKTLPGEETEATTSTASGINPGQAQ 490
            |..|:.:|..|||.::.:||...               |:|.|||
Human   371 FLNLMHHNQQVFGPYYAEILKHI---------------IHPAQAQ 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16721	NP_001284913.1	Tcp11	69..460	CDD:283456	105/403 (26%)
TCP11X1	NP_001355087.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1230328at2759
OrthoFinder	1	1.000	-	-		FOG0000982
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850