Protein Alignment Usp30 and UBP12

DIOPT Version :10

• Sequence 1: NP_572274.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_012338.1
• Gene: UBP12 / 853242
• SGDID: S000003733
• Length: 1254
• Species: Saccharomyces cerevisiae
• Alignment Length: 618
• Identity: 121/618 - (19%)
• Similarity: 190/618 - (30%)
• Gaps: 198/618 - (32%)

  Fly    31 LRQRRGQIAGLHN---FGLTCFLNTL---LQAMAACPQFIAWLQL---------YNNASPDRKSL 80
            |:...|:::||..   ||...|.|.:   .::..:..||:...:|         |.....:...:
Yeast   591 LKNYVGKMSGLDPNTLFGCEIFSNQIYVNYESTESNAQFLTLQELIKPADDVIFYELPVTNDNEV 655

  Fly    81 ITSMLNTLEVVNGTHATLRGDPY----------SPGAVL-----RALNALGWVIPQEEHDAHELF 130
            |..:|||.......:|.|.|.|:          :|||:.     |.::..|..||
Yeast   656 IVPVLNTRIEKGYKNAMLFGVPFFITLKEDELNNPGAIRMKLQNRFVHLSGGYIP---------- 710

  Fly   131 HVLLTCLEEEAIRPQPLG---CLSDALP-------------------------TDNDDNSSLAGT 167
                        .|:|:|   ..:||.|                         ||.|.:
Yeast   711 ------------FPEPVGNRTDFADAFPLLVEKYPDVEFEQYKDILQYTSIKVTDKDKS------ 757

  Fly   168 ATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAMLTDFLNMEYDEST----SLQRLVRSEAHTPD 228
                    .||.....:...|:.... ||......|....:..|::|    .|:.:|: :.:...
Yeast   758 --------FFSIKILSVEKEQQFASN-NRTGPNFWTPISQLNLDKATDIDDKLEDVVK-DIYNYS 812

  Fly   229 SPASVCERDGNDRLGSVLLDAVSPGTPFGFPLVSNPDSLATPMLGGERSSRPRLPQSQQ------ 287
            |.....|        .||:.....|...|    |...:.:.|...|:.........:.:
Yeast   813 SLVDCAE--------GVLMQVDDEGDTEG----SEAKNFSKPFQSGDDEENKETVTNNENVNNTN 865

  Fly   288 --QQDEGLNRRVSSSCRSLERLHRGPGRVSIWSNMMPSQVAHPFQ-GAMGAQIVC--NGCGSKSA 347
              .:|..|...|.....:...|...|..:   ..:..|..:.||. .:|...|||  :..||..|
Yeast   866 DRDEDMELTDDVEEDASTEPELTDKPEAL---DKIKDSLTSTPFAILSMNDIIVCEWSELGSNEA 927

  Fly   348 VRYDKF----DSITLNLPPQRRTGLSLGHLLSEYITSED------------LSDV-KCDSCNETT 395
            ...||.    :..||.........|...:.....||.:|            |:|. .|.:|.|..
Yeast   928 FSDDKIYNWENPATLPNKELENAKLERSNAKERTITLDDCLQLFSKPEILGLTDSWYCPTCKEHR 992

  Fly   396 THTKSVTFAKLPACLCIHVARTVWLPTGQVCKRKDY-------VHFP-ESLSMAPYSFVQPHLNS 452
            ..||.:.....|..|.||:.|..        .::.:       |:|| ..|.::.|
Yeast   993 QATKQIQLWNTPDILLIHLKRFE--------SQRSFSDKIDATVNFPITDLDLSRY--------- 1040

  Fly   453 QAGTPWGSTMSLYSSSLPMNNGVGGGEGFGTMFPKNL-YRLLAVVVHSGEANSGHFVTYRRGSLR 516
                      .:|...                 |:.| |.|.||..|.|....||:..|.:....
Yeast  1041 ----------VVYKDD-----------------PRGLIYDLYAVDNHYGGLGGGHYTAYVKNFAD 1078

  Fly   517 NAHRWYYTSDTIVREVSIDEVLSVPAYLLFYDR 549
            |  :|||..|:.|.|.:.:..::..||||||.|
Yeast  1079 N--KWYYFDDSRVTETAPENSIAGSAYLLFYIR 1109

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_572274.1	Peptidase_C19	39..>139	CDD:470612	25/129 (19%)
		Peptidase_C19F	<323..548	CDD:239127	59/253 (23%)
UBP12	NP_012338.1	UBP12	99..1111	CDD:227847	121/618 (20%)