Protein Alignment Usp30 and UBP1

DIOPT Version :9

• Sequence 1: NP_001284912.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_010161.1
• Gene: UBP1 / 851435
• SGDID: S000002280
• Length: 809
• Species: Saccharomyces cerevisiae
• Alignment Length: 773
• Identity: 141/773 - (18%)
• Similarity: 220/773 - (28%)
• Gaps: 364/773 - (47%)

  Fly    24 WGPSG------SRLRQRRGQIAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNASPDRKSLIT 82
            |.|..      ..:.:|.|.||||.|.|.|||:|::||::|:..:.:.:|.  ||
Yeast    80 WLPRSKFTHLDEEILKRGGFIAGLVNDGNTCFMNSVLQSLASSRELMEFLD--NN---------- 132

  Fly    83 SMLNTLEVVNGTHATLRGDPYSPGAVLRALNALGWVIPQEEHDAHELFHVLLTCLEEEAIRPQPL 147
             ::.|.|                            .|.|.||:
Yeast   133 -VIRTYE----------------------------EIEQNEHN---------------------- 146

  Fly   148 GCLSDALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAMLTDFLNMEYDE 212
                    .:.:...|....||.....|....:   .|..::   :.||.||:        :.||
Yeast   147 --------EEGNGQESAQDEATHKKNTRKGGKV---YGKHKK---KLNRKSSS--------KEDE 189

  Fly   213 STSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVSP----GTPFGFPLVSNPDSLATPMLG 273
            ..|.:         ||...||..||        ||.|::.    ..|:     ...:||...|
Yeast   190 EKSQE---------PDITFSVALRD--------LLSALNAKYYRDKPY-----FKTNSLLKAM-- 230

  Fly   274 GERSSRPRLPQSQQQQD-----EGLNRRVSSSCRSL--ERLHRGP------------GRVSIW-- 317
             .:|.|..:.....|:|     :.:...:.|:.:||  |:|...|            |::::.
Yeast   231 -SKSPRKNILLGYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVAKSELPDDALVGQLNLGEV 294

  Fly   318 ---------------------SNMMPSQVAHPFQGAMGAQIVCNGCGSKSAVRYDKFDSITLNLP 361
                                 .|..|.::..|..|....:|.|..||....:||..|..::||||
Yeast   295 GTVYIPTEQIDPNSILHDKSIQNFTPFKLMTPLDGITAERIGCLQCGENGGIRYSVFSGLSLNLP 359

  Fly   362 PQR-RTGLSLGHLLSEYITSEDLSDVKCDSCNETTTH---------------------------- 397
            .:. .:.|.|..|||::...|.:..|:|:.|..|..|
Yeast   360 NENIGSTLKLSQLLSDWSKPEIIEGVECNRCALTAAHSHLFGQLKEFEKKPEGSIPEKLINAVKD 424

  Fly   398 ---------------------------------TKSVTFAKLPACLCIHVARTVWLP-TGQVCKR 428
                                             :|.:..::.|..|.||:.|:|:.| |..:.|.
Yeast   425 RVHQIEEVLAKPVIDDEDYKKLHTANMVRKCSKSKQILISRPPPLLSIHINRSVFDPRTYMIRKN 489

  Fly   429 KDYVHFPESLSMAPYSFVQPHLNSQAGTPW----------------------------------- 458
            ...|.|...|::||:......:|..|..|.
Yeast   490 NSKVLFKSRLNLAPWCCDINEINLDARLPMSKKEKAAQQDSSEDENIGGEYYTKLHERFEQEFED 554

  Fly   459 -----------GSTMSLY------SSSLPMNNGVGG------------GEGFGTMFPKNL----- 489
                       |:..|.|      |:..|:|..|.|            .:..|....|.:
Yeast   555 SEEEKEYDDAEGNYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYIEETDALGNTIKKRIIEHSD 619

  Fly   490 -------------------------------------------------------------YRLL 493
                                                                         |.|.
Yeast   620 VENENVKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVIPAPPINYARSFSTVPATPLTYSLR 684

  Fly   494 AVVVHSGEANSGHFVTYR--RGSLRNAHRWYYTSDTIVREVSIDEVLSVP-AYLLFYD 548
            :|:||.|..|.||::.:|  ||.      |:..||..|..|...||||.| .::|||:
Yeast   685 SVIVHYGTHNYGHYIAFRKYRGC------WWRISDETVYVVDEAEVLSTPGVFMLFYE 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_001284912.1	Peptidase_C19	39..>139	CDD:271592	21/99 (21%)
		UCH	<304..547	CDD:278850	82/475 (17%)
		Peptidase_C19F	<323..548	CDD:239127	76/420 (18%)
UBP1	NP_010161.1	Peptidase_C19	101..>293	CDD:351799	57/301 (19%)
		Peptidase_C19F	102..736	CDD:239127	134/749 (18%)
		Peptidase_C19	<427..>510	CDD:351799	15/82 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I1255
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104100
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3964
TreeFam	0	0.000	Not matched by this tool.
	5	4.800