Protein Alignment Usp30 and Usp44

DIOPT Version :10

• Sequence 1: NP_572274.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001193780.1
• Gene: Usp44 / 327799
• MGIID: 3045318
• Length: 711
• Species: Mus musculus
• Alignment Length: 565
• Identity: 116/565 - (20%)
• Similarity: 186/565 - (32%)
• Gaps: 216/565 - (38%)

  Fly    38 IAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNASPDRKSLITSMLNTLEVVNGTHATLRGDP 102
            :.||.|.|.||::|::||.::....|             |:..:...||.
Mouse   271 VTGLRNLGNTCYMNSVLQVLSHLLIF-------------RQCFLKLDLNQ--------------- 307

  Fly   103 YSPGAVLRALNALGWVIPQEEHDAHELFHVLLTCLEEEAIRPQPLGCLSDALPTDNDDNSSLAG- 166
                          |:.......|....|..:|    ||...|.           |:......|
Mouse   308 --------------WLAVAASDKARSYKHSAVT----EAAAQQM-----------NEGQEKEKGF 343

  Fly   167 TATPVGGFRSFSSMAAGLGASQRIGDQPNRPSS---------------------AMLTDFLNMEY 210
            ..:...|..|..|..|..|.:..: .||..|||                     |:::.|..:.
Mouse   344 VCSRHSGLSSGLSGGASKGRNMEL-IQPREPSSPYSSLCHELHILFQVMWSGEWALVSPFAMLH- 406

  Fly   211 DESTSLQRLV---RSEAHTPDSPASVCERDGNDRLGSVLLDAV-----SPGTPFGFPLVSNPDSL 267
                |:.||:   |..|. .|:...:||          |||.:     :.||..
Mouse   407 ----SVWRLIPAFRGYAQ-QDAQEFLCE----------LLDKIQRELETTGTKL----------- 445

  Fly   268 ATPMLGGERSSRPRLPQSQQQQDEGLNRRVSSSCRSLERLHRGPGRVSIWSNMMPSQVAHPFQGA 332
              |.|         :|.||:              |.:|::      :::.:|:        |.|.
Mouse   446 --PAL---------IPTSQR--------------RLIEQV------LNVVNNI--------FHGQ 471

  Fly   333 MGAQIVCNGCGSKSAVRYDKFDSITLNLPPQRRTG--------LSLGHLLSEYITSEDLSD--VK 387
            ..:|:.|..|.:||.. .:.|..::|..|.:.:..        ..:..:|.::..:|.|..  ..
Mouse   472 FLSQVTCLACDNKSDT-IESFWDLSLEFPERYQCSGKDAASQPCLVTDMLDKFTETEALEGKIYM 535

  Fly   388 CDSCNETTT--HTKSVTFAK---------LPACLCIHVARTVWLPTGQVCKRKDYVH--FPESLS 439
            ||.||....  .:|||.|.:         ||..|.:|:.|..|  :|:..:.|..||  |.|:|:
Mouse   536 CDHCNSKRRKFSSKSVVFTEAQKQLMICHLPQVLRLHLKRFRW--SGRNNREKIGVHVVFEETLN 598

  Fly   440 MAPYSFVQPHLNSQAGTPWGSTMSLYSSSLPMNNGVGGGEGFGTMFPK-NLYRLLAVVVHSGEA- 502
            |.||..                                .|....:.|: .||.|.|||:|.|:.
Mouse   599 MEPYCC--------------------------------RETLNALRPECFLYNLSAVVIHHGKGF 631

  Fly   503 NSGHFVTYRRGSLRNAHRWYYTSDTIVREVSIDEVLSVPAYLLFY 547
            .|||:..|...|  ....|.:.:|:.:...:::||....||:|||
Mouse   632 GSGHYTAYCYNS--EGGFWVHCNDSKLSMCTMEEVRKAQAYILFY 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_572274.1	Peptidase_C19	39..>139	CDD:470612	17/99 (17%)
		Peptidase_C19F	<323..548	CDD:239127	61/250 (24%)
Usp44	NP_001193780.1	zf-UBP	26..88	CDD:460464
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..251
		UCH	272..674	CDD:425685	114/562 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	685..711