Protein Alignment Usp30 and Usp49

DIOPT Version :10

• Sequence 1: NP_572274.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_940813.1
• Gene: Usp49 / 224836
• MGIID: 2685391
• Length: 685
• Species: Mus musculus
• Alignment Length: 590
• Identity: 122/590 - (20%)
• Similarity: 187/590 - (31%)
• Gaps: 236/590 - (40%)

  Fly    27 SGSRLRQRRGQ-----IAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNASPDRKSLITSMLN 86
            |.:.|..||..     :.||.|.|.||::|::||.::...:|   .:.:.|..|.     ||...
Mouse   233 SAAALNPRRQPAVAPGVTGLRNLGNTCYMNSILQVLSHLQKF---RECFLNLDPS-----TSEHL 289

  Fly    87 TLEVVNGTHATLRGDPYSPGAV---LRALNALG-------W-----------VIPQEE------- 123
            ..:..|| .|.|.|.|.|..|.   :|::.|.|       |           :|..:|
Mouse   290 FPQATNG-KAQLSGRPASSSAAELSVRSVRAQGCEPQGLCWSSGASISRSLELIQNKEPSSKHIS 353

  Fly   124 --HDAHELFHVLLTCLEEEAIRPQPLGCLSDALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGA 186
              |:.|.||.|:                              .:|....|..|....|:.:.:.|
Mouse   354 LCHELHTLFRVM------------------------------WSGKWALVSPFAMLHSVWSLIPA 388

  Fly   187 SQRIGDQPNRPSSAMLTDFLNMEYDESTSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVS 251
            .:                    .||:.              |:...:||          ||..|
Mouse   389 FR--------------------GYDQQ--------------DAQEFLCE----------LLHKV- 408

  Fly   252 PGTPFGFPLVSNPDSLATPMLGGERSSRPRLPQSQQQQDEGLNRR--VSSSCRSLERLHRGPGRV 314
                                             .|:.:.||..||  :..|.|.|
Mouse   409 ---------------------------------QQELESEGSTRRILIPFSQRKL---------- 430

  Fly   315 SIWSNMMPSQVAHPFQGAMGAQIVCNGCGSKSAVRYDKFDSITLNLP-----------PQRRTGL 368
               :..:...|...|.|.:.:|:.|..|..||.. .:.|..::|..|           |..:|..
Mouse   431 ---TKQVLKVVNTIFHGQLLSQVTCISCNYKSNT-IEPFWDLSLEFPERYHCIEKGFVPLNQTEC 491

  Fly   369 SLGHLLSEYITSEDLSD--VKCDSCNETTTHT-----------KSVTFAKLPACLCIHVARTVWL 420
            .|..:|:::..:|.|..  ..||.||.....:           |.:...:||..|.:|:.|..|
Mouse   492 LLTEMLAKFTETEALEGRIYACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLRLHLKRFRW- 555

  Fly   421 PTGQVCKRKDYVH--FPESLSMAPYSFVQPHLNSQAGTPWGSTMSLYSSSLPMNNGVGGGEGFGT 483
             :|:..:.|..||  |.:.|:|.||                ....:.||.        ..|.|.
Mouse   556 -SGRNHREKIGVHVIFDQVLTMEPY----------------CCRDMLSSL--------DKETFA- 594

  Fly   484 MFPKNLYRLLAVVVHSGEA-NSGHFVTY---RRGSLRNAHRWYYTSDTIVREVSIDEVLSVPAYL 544
                  |.|.|||:|.|:. .|||:..|   ..|..     |.:.:|:.:...|::||....||:
Mouse   595 ------YDLSAVVMHHGKGFGSGHYTAYCYNTEGGF-----WVHCNDSKLDVCSVEEVCKTQAYI 648

  Fly   545 LFYDR 549
            |||.|
Mouse   649 LFYTR 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_572274.1	Peptidase_C19	39..>139	CDD:470612	33/129 (26%)
		Peptidase_C19F	<323..548	CDD:239127	62/254 (24%)
Usp49	NP_940813.1	zf-UBP	26..87	CDD:460464
		UCH	250..651	CDD:425685	115/569 (20%)