DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp30 and C34F6.9

DIOPT Version :9

Sequence 1:	NP_001284912.1	Gene:	Usp30 / 31519	FlyBaseID:	FBgn0029819	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001366881.1	Gene:	C34F6.9 / 181312	WormBaseID:	WBGene00007943	Length:	1181	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	68/350 - (19%)
Similarity:	113/350 - (32%)	Gaps:	85/350 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 EAIRPQPLGCLS-DALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAMLT 203
            |.:.||.|..|. .:||.||...|....::.    .::.::..|.......:.|:..:..|..|.
Worm   724 ETVSPQELHSLKRKSLPDDNTTPSKQRRSSR----LKNSTAKTADFVYEPAVTDRSEQDKSPSLP 784

  Fly   204 DFLNMEYDESTSLQRLVRSEAHTPDSPAS-----------------VCERDGNDRLGSVLLDAVS 251
            ...|:..|...|.....||.:....:|.|                 ...|..|:.:.|:|...::
Worm   785 REKNIGKDSGKSRLASQRSSSRRSSAPFSEESPSTKKTRFSTRVEQYSRRVSNETIKSLLQQVLT 849

  Fly   252 PGTP--------FGFPLVS----NPDSL--ATPMLGGERSSRPRLPQ------SQQQQDEGLNRR 296
            |...        |..|:|.    |.::|  |..|:    ....|:||      |...:.:..||.
Worm   850 PKAADECDIQDHFPSPIVRRAIVNRNTLCYAISMV----QLLMRVPQVYSIVRSHSHKKQKANRS 910

  Fly   297 VSSSC------RSLERLHRGPGRVSI----WSNMMPSQV--------------------AHP--- 328
            ....|      ....|....|..|::    |.|:....:                    |||
Worm   911 ECFLCMLTNLISERPRADDTPAFVALLKSNWKNIEDEGMQCVMEAMQYFFNKFDEEYMHAHPPIR 975

  Fly   329 --FQGAMGAQIVCNGCGSKSAVRYDKFDSITLNLPPQRRTGLSLGHLLSEYITSEDLSDVKCDSC 391
              |:..|.....|..|...|... ||...::::|  ..:|..::..::.:......:..:.|.||
Worm   976 SYFEIEMFIAYECKSCKHVSNAP-DKAIYVSIDL--SSKTKGTMQSMVDKMANPIPVVGMNCKSC 1037

  Fly   392 NETTTHTKSVTFAKLPACLCIHVAR 416
            .:.|. ..:..|.|||..|...|.|
Worm  1038 GQETL-CSTTRFTKLPEVLLYFVPR 1061

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_001284912.1	Peptidase_C19	39..>139	CDD:271592
		UCH	<304..547	CDD:278850	27/141 (19%)
		Peptidase_C19F	<323..548	CDD:239127	22/118 (19%)
C34F6.9	NP_001366881.1	Peptidase_C19	949..1130	CDD:239072	22/116 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900