Protein Alignment Usp30 and duo-3

DIOPT Version :9

• Sequence 1: NP_001284912.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001293463.1
• Gene: duo-3 / 172925
• WormBaseID: WBGene00001112
• Length: 924
• Species: Caenorhabditis elegans
• Alignment Length: 686
• Identity: 122/686 - (17%)
• Similarity: 215/686 - (31%)
• Gaps: 243/686 - (35%)

  Fly    41 LHNFGLTCFLNTLLQAMAACPQFIAWLQLYNN---------ASPDRK-------SLITSMLNTLE 89
            |:|.|.:|:.|:.:||:::||..::..::.:.         .|.|.:       |.:..|:...:
 Worm   304 LYNTGNSCYFNSTMQALSSCPSLVSRFEMLHRLRHGNYLECPSYDLRPKFAVFESCLRMMVKLSD 368

  Fly    90 VVNGTH-ATLRGDPYSPGAVLRALNALGWVIPQ----EEHDAHELFHVLLTCLE-------EEAI 142
            .:...| ...|...:|...:......:|.|:.:    ::.||||....||:|::       :|..
 Worm   369 RMENPHLKEYRLPSFSETELANTRLKIGRVVKEFDNNDQKDAHEYLTELLSCVDDIMQVVPDEIK 433

  Fly   143 RPQPLG-----------CLSDALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNR 196
            ...||.           |.:    ..:::.||..|...|:    |.|:...|
 Worm   434 HLDPLNSIRYKTERSFICFN----CGHEEKSSDCGWILPL----SISNNDYG------------- 477

  Fly   197 PSSAMLTDFLNMEYDESTSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVSPGTPFGFP-- 259
                 :.:.|...:..:....::..|         ..||            :|||......||
 Worm   478 -----IIELLESNFKTTLETNKICSS---------CSCE------------NAVSSERIANFPEC 516

  Fly   260 LVSNPDSLATPMLGGERSSRPRLPQ------------SQQQQDEGLNRRVSSSCRSLERLHR--- 309
            |:.||.......:...|....::..            :..:|||..|.....||......:|
 Worm   517 LILNPMRYERTSISDYRKDNRQITVPLTLDLTRFGAFASLEQDENRNSVSFGSCGKDSIKYRNGP 581

  Fly   310 --GPGRVS----------IWSNMMPSQVAHPFQGAM---------------------GAQIVCNG 341
              ||..:|          |...||...|.:|.....                     ..:|....
 Worm   582 SIGPRLLSLNGGSLDDEEIDIEMMKEVVKNPLHFKWLTDLDEIEQMLKLTNITYRRDDVKIHVEK 646

  Fly   342 CGSKSAVRYDKFD-----------------SITLNLPPQRRTGLSLGHLLSEYITSE-DLSDVKC 388
            ..::.:|...|||                 :|:..|...::...:|....:.|:.:: .:.|..|
 Worm   647 LENEKSVVMKKFDRPGRVKGIESDGNCFYRAISWCLTGSQKYHKALRIATANYLRNDIAIVDKYC 711

  Fly   389 DSCNETT------------THTKSVTFAKLPACLCIHVARTVWLPTGQVC--------------- 426
            ...:..|            |:.:....|.|     ::|....:|..|.:|
 Worm   712 HKTDHKTYVQQVEGDGWWATNVEICVMANL-----LNVNIYTFLSDGWICTSPQNSSTSRSGSFY 771

  Fly   427 -KRKDYVHFPESLSMAPYSFVQPHLNSQAGTPWGSTMSLYSSSLPMNNGVGGG------EGFGTM 484
             :.|| .|:...||:.....::........|.:            .::..|||      :...:.
 Worm   772 LENKD-CHYEPVLSLKKDDSLRSRKRRNTDTEY------------TDDNEGGGFKKRKPDDDASR 823

  Fly   485 FPKNL--------------------------------YRLLAVVVHSGE-ANSGHFVTYRRGSLR 516
            .|:||                                |||.|.:.|.|| .:.||::...| .|.
 Worm   824 KPRNLSESERRRQPPRDAEDNGNHYKKMNANTDQIAKYRLFAAICHIGEFPDRGHYLALTR-DLY 887

  Fly   517 NAHRWYYTSDTIVREVSIDEVL---SVPAYLLFYDR 549
            |..:|...||.:||::|..:|:   |...|||||||
 Worm   888 NPSKWLDCSDAVVRDISSGDVIKDASSSGYLLFYDR 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_001284912.1	Peptidase_C19	39..>139	CDD:271592	25/125 (20%)
		UCH	<304..547	CDD:278850	63/366 (17%)
		Peptidase_C19F	<323..548	CDD:239127	57/333 (17%)
duo-3	NP_001293463.1	Peptidase_C19Q	303..>554	CDD:239138	49/296 (17%)
		Peptidase_C19	304..>426	CDD:271592	25/121 (21%)
		OTU	669..786	CDD:303090	19/122 (16%)
		Peptidase_C19	<812..922	CDD:271592	27/110 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1437269at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920