Protein Alignment Usp30 and USP51

DIOPT Version :9

• Sequence 1: NP_001284912.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_958443.1
• Gene: USP51 / 158880
• HGNCID: 23086
• Length: 711
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 102/547 - (18%)
• Similarity: 160/547 - (29%)
• Gaps: 238/547 - (43%)

  Fly    38 IAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNASPDRKSLIT--SMLNTLEVVNGTHATLRG 100
            :.||.|.|.|||:|.::||:...|....:.     .|...|.::|  |:....|:.:..||...|
Human   362 LRGLINLGNTCFMNCIVQALTHIPLLKDFF-----LSDKHKCIMTSPSLCLVCEMSSLFHAMYSG 421

  Fly   101 D--PYSPGAVLRALNALGWVIPQEEH-------DAHELFHVLLTCLEEEAIRPQPLGCLSDALPT 156
            .  |:.|..:|..:    |:  ..||       ||||....:|                 |.|..
Human   422 SRTPHIPYKLLHLI----WI--HAEHLAGYRQQDAHEFLIAIL-----------------DVLHR 463

  Fly   157 DNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAMLTDFLNMEYDESTSLQRLVR 221
            .:.|:|
Human   464 HSKDDS----------------------------------------------------------- 469

  Fly   222 SEAHTPDSPASVCERDGNDRLGSVLLDAVSPGTPFGFPLVSNPDSLATPMLGGERSSRPRLPQSQ 286
                                                               ||:.::.|
Human   470 ---------------------------------------------------GGQEANNP------ 477

  Fly   287 QQQDEGLNRRVSSSCRSLERLHRGPGRVSIWSNMMPSQVAHPFQGAMGAQIVCNGCGSKSAVRYD 351
                         :|                .|.:..|:   |.|.:.:.:.|..|.|.|.. .|
Human   478 -------------NC----------------CNCIIDQI---FTGGLQSDVTCQACHSVSTT-ID 509

  Fly   352 KFDSITLNLP----------PQRRTGL-----------SLGHLLSEYITSEDL---SDVKCDSCN 392
            ....|:|:||          |:|....           ||...|..:...|.|   :.:||:||.
Human   510 PCWDISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQ 574

  Fly   393 ETTTHTKSVTFAKLPACLCIHVARTVWLPTGQVCKRKDYVHFPESLSMAPYSFVQPHLNSQAGTP 457
            .....||.:|..|||...|.|:.|...:.. |..|...::.||..|.|.|:.........:.|.|
Human   575 SYQESTKQLTMKKLPIVACFHLKRFEHVGK-QRRKINTFISFPLELDMTPFLASTKESRMKEGQP 638

  Fly   458 WGSTMSLYSSSLPMNNGVGGGEGFGTMFPKNLYRLLAVVVHSGEANSGHFVTYRRGSLRNAHRWY 522
                   .:..:|               .:|.|.|.||:.|.|...|||:.::.|   :...:|:
Human   639 -------PTDCVP---------------NENKYSLFAVINHHGTLESGHYTSFIR---QQKDQWF 678

  Fly   523 YTSDTIVREVSIDEVLSVPAYLLFYDR 549
            ...|.|:.:.:|:::|....|||||.:
Human   679 SCDDAIITKATIEDLLYSEGYLLFYHK 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_001284912.1	Peptidase_C19	39..>139	CDD:271592	30/110 (27%)
		UCH	<304..547	CDD:278850	62/266 (23%)
		Peptidase_C19F	<323..548	CDD:239127	62/248 (25%)
USP51	NP_958443.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..174
		zf-UBP	236..296	CDD:280334
		UCH	362..703	CDD:278850	100/543 (18%)
		Peptidase_C19D	363..704	CDD:239125	101/543 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810