Protein Alignment Usp30 and Usp30

DIOPT Version :9

• Sequence 1: NP_001284912.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001028374.1
• Gene: Usp30 / 100756
• MGIID: 2140991
• Length: 517
• Species: Mus musculus
• Alignment Length: 610
• Identity: 163/610 - (26%)
• Similarity: 233/610 - (38%)
• Gaps: 219/610 - (35%)

  Fly    11 GVTVAAVVGAFVFWGPSGSRLRQRRGQIAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNA-S 74
            |:..|...|.:|.|||...|.::|:|.:.||.|.|.|||:|:|||.::|||.|:.||:.:... |
Mouse    40 GIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYS 104

  Fly    75 PDRKS------LITSMLNTLEVVNGTHATLRGDPYSPGAVLRALNALGWVIPQ-EEHDAHELFHV 132
            .|::.      |..::||.|:.::....| ..:......:|..|....|.|.. ||.||||||||
Mouse   105 RDQQGPHTHQCLSLTLLNLLKALSCQEVT-EDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHV 168

  Fly   133 LLTCLEEEAIRPQPLGCLSDALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNRP 197
            :.:.||:
Mouse   169 ITSSLED---------------------------------------------------------- 175

  Fly   198 SSAMLTDFLNMEYDESTSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVSPGTPFGFPLVS 262
                                                 |||...|: :.|.|.
Mouse   176 -------------------------------------ERDRQPRV-THLFDV------------- 189

  Fly   263 NPDSLATPMLGGERSSRPRLPQSQQQQDEGLNRRVSSSCRSLERLHRGPGRVSIWSNMMPSQVAH 327
                                 .|.:||.|...|:|:...|         |.....:|...||  |
Mouse   190 ---------------------HSLEQQSEMAPRQVTCHTR---------GSPHPTTNHWKSQ--H 222

  Fly   328 PFQGAMGAQIVCNGCGSKSAVRYDKFDSITLNLP------PQRRTGLSLGHLLSEYITSEDLSDV 386
            ||.|.:.:.:||..|..:|.||:|.|||::|::|      |     |:|.|.|..:|:||.:.||
Mouse   223 PFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHP-----LTLDHCLHHFISSESVRDV 282

  Fly   387 KCDSC---------------NETTTHTKSVTFAKLPACLCIHVARTVWLPTGQVCKRKDYVHFPE 436
            .||:|               ::.:|..|.:...|||.|||||:.|..|...|...||.::|.|.|
Mouse   283 VCDNCTKIEARGTLTGEKVEHQRSTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNE 347

  Fly   437 SLSMAPYSF-VQPHLNSQAG-----TPWGSTMSLYSSSLPMNNGVG-----------GGEGFGTM 484
            .|.|..|.: :..|..||.|     .| ||...:..:......|:.           .|....::
Mouse   348 FLMMDFYKYRLLGHKPSQHGPKATENP-GSAPEVQDAQAAPKPGLSQPGAPKTQIFLNGACSPSL 411

  Fly   485 FP-------------------KNLYRLLAVVVHSGEANSGHFVTYRR------GSLRNAHRWYYT 524
            .|                   ..|:||:|||||.|:.:|||||||||      ..|..:::|.:.
Mouse   412 LPALPSPVAFPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWI 476

  Fly   525 SDTIVREVSIDEVLSVPAYLLFYDR 549
            ||..||:.|:.||||..||||||:|
Mouse   477 SDDTVRKASLQEVLSSSAYLLFYER 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp30	NP_001284912.1	Peptidase_C19	39..>139	CDD:271592	39/107 (36%)
		UCH	<304..547	CDD:278850	97/305 (32%)
		Peptidase_C19F	<323..548	CDD:239127	96/287 (33%)
Usp30	NP_001028374.1	Peptidase_C19F	69..500	CDD:239127	114/465 (25%)
		UCH	69..499	CDD:278850	114/464 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..221		0/22 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..395		13/36 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835910
Domainoid	1	1.000	140	1.000	Domainoid score	I4751
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32789
Inparanoid	1	1.050	143	1.000	Inparanoid score	I4444
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58493
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004826
OrthoInspector	1	1.000	-	-		oto95127
orthoMCL	1	0.900	-	-		OOG6_104100
Panther	1	1.100	-	-	LDO	PTHR24006
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4233
SonicParanoid	1	1.000	-	-		X3964
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790