Protein Alignment mof and KAT6A

DIOPT Version :9

• Sequence 1: NP_511051.1
• Gene: mof / 31518
• FlyBaseID: FBgn0014340
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_011542958.1
• Gene: KAT6A / 7994
• HGNCID: 13013
• Length: 2048
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 189/570 - (33%)
• Similarity: 291/570 - (51%)
• Gaps: 109/570 - (19%)

  Fly   275 YLSPYIR--SRYMQEST----PGLPTRLAPRDPRQRNMPPPAVVLPIQTVLSANVEAISDDSSET 333
            |.:|..|  :|..:::|    |....|..|...|:|.:           .||:        .|.:
Human   331 YTNPIGRPKNRLKKQNTVSKGPFSKVRTGPGRGRKRKI-----------TLSS--------QSAS 376

  Fly   334 SSSDDDEEEEED-----EDDALTMEHDNTSRETVITTGDPLMQKIDISENPDKIYFIRREDGTVH 393
            |||::...|..|     .|..::::.:..::..:    |.|.:           :|....||...
Human   377 SSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLI----DGLTK-----------FFTPSPDGRKA 426

  Fly   394 RGQVLQSRTTENAAAPDEYYVHYVGLNRR----------LDGWVGRHRISDNADDLGGITVLPAP 448
            ||:|:.        ..::|.:...| ||:          .|||.|:   .:|.:.|.|
Human   427 RGEVVD--------YSEQYRIRKRG-NRKSSTSDWPTDNQDGWDGK---QENEERLFG------- 472

  Fly   449 PLAPDQPSTSREM-----LAQQAAAAAAASSERQKRAANKDYYLSYCENSRYDYSDRKMTRYQKR 508
               ..:..|.::|     :.:||....|.              :..|:...:::..   |.....
Human   473 ---SQEIMTEKDMELFRDIQEQALQTCAV--------------VVMCKQLYWNWIS---TFTSGI 517

  Fly   509 RYDEINHVQKSHAELTATQAALEKEHESIT-----KIKYIDKLQFGNYEIDTWYFSPFPEEYGKA 568
            |.:|    |::....|..|..:.::...:|     :::....::||.|||.|||.||:|:||.:.
Human   518 RLEE----QRAADGKTLKQQTVPQQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRL 578

  Fly   569 RTLYVCEYCLKYMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKL 633
            ..||:||:|||||:.|:....|:.:|....||..|||||.|||::||:|...::|||.|||:|||
Human   579 PKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKL 643

  Fly   634 FLDHKVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIA 698
            |||||.||:|::|||||:|.:.|.:|.|:||||||||...:.|||:||::||.:||||:|:.||.
Human   644 FLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLID 708

  Fly   699 FSYELSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPEQITIKELSEMSGITHDDII 763
            |||.||::||..|||||||||||||||.:||...:||.:..: ..:||:||:||:::||...||.
Human   709 FSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQ-NDKQISIKKLSKLTGICPQDIT 772

  Fly   764 YTLQSMKMIKYWKGQNVICVTSKTIQDHLQLPQFKQPKLTIDTDYLVWSP 813
            .||..::|:.:...|.||....|.||||:...|.....:.:|.:.|.|:|
Human   773 STLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTP 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	Tudor-knot	382..432	CDD:288553	14/59 (24%)
		NAT_SF	528..813	CDD:302625	138/289 (48%)
		MOZ_SAS	599..778	CDD:280097	100/178 (56%)
KAT6A	XP_011542958.1	H15	85..162	CDD:197772
		PHD1_MOZ_MORF	205..262	CDD:277090
		PHD2_KAT6A_6B	264..310	CDD:277002
		NAT_SF	549..823	CDD:302625	138/275 (50%)
		MOZ_SAS	609..787	CDD:280097	100/178 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820