DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mof and Samd1

DIOPT Version :9

Sequence 1:	NP_511051.1	Gene:	mof / 31518	FlyBaseID:	FBgn0014340	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001074884.1	Gene:	Samd1 / 666704	MGIID:	2142433	Length:	519	Species:	Mus musculus

Alignment Length:	482	Identity:	97/482 - (20%)
Similarity:	141/482 - (29%)	Gaps:	185/482 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 PPAKRQHRDISPISEDSTPASSTSTSSTRSSSSSRYD-------DVSEAEEAPPE---------- 130
            |||      :.|  .::..|::|:.:::.|::|..|.       |...:.:|.|:
Mouse     4 PPA------LPP--PETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRR 60

  Fly   131 ---PEPEQPQQQQQEEKKEDGQDQVKSPGPVELEAQEPAQPQKQKEVVDQEIETEDEPSSDTVIC 192
               ||||:.:.:.::..::....:|...|.:........||.::...         .|:...|
Mouse    61 RHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGAT---------PPAPPRV-- 114

  Fly   193 VADINPYGSGSNIDDFVMDPDAP-------PNAIITEVVTIPAPLHLKGTQQLGLPLAAPPPPP- 249
                 |.|..:........|.||       |.|........|.|.......|...|||||||.|
Mouse   115 -----PRGGPAAPPPTPAPPPAPVAAPTRAPRAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPA 174

  Fly   250 --------------PPPAAEQVPETPASPTDDGEEPP------------------AVYLSPYIR- 281
                          ||||. ...|.||.|......||                  .|.|...:|
Mouse   175 APPAAAPPAGPRRAPPPAV-AAREPPAPPQQQQPPPPQPQPPPEGGAARAGGPARPVSLREVVRY 238

  Fly   282 --------SRYMQESTPGL-----------PTRLA----PRDPRQRNMPPPAVVLPIQTVLSANV 323
                    .|..:....||           .|||.    ||..|....||.|         ||..
Mouse   239 LGGSGGASGRLTRGRVQGLLEEEAARGRLERTRLGALALPRGDRPGRAPPAA---------SARA 294

  Fly   324 EAISDDSSETSSSDDDEEEEEDEDDALTMEHDNTSRETVITTGDPLMQKIDISENPDKIYFIRRE 388
            ........|.....::|:|:|||::.   |.||.|..:.:...|                   |.
Mouse   295 ARSKRGGEERVFEKEEEDEDEDEEEE---EEDNVSEGSEVPESD-------------------RP 337

  Fly   389 DGTVHRGQVLQSRTTENAAAPDEYYVHYVGLNRRLDGW--VGRHRISDNADDLGGITVLPAP--- 448
            .|..|. |:...|..::|             ..|:..|  .|.::..|....       |||
Mouse   338 AGAQHH-QINGERGPQSA-------------KERVKEWSPCGPYQGQDEGRG-------PAPGSC 381

  Fly   449 -----PL--------------APDQPS 456
                 |:              |||.||
Mouse   382 TRQVFPMTAVNKEGGSACVGAAPDSPS 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	Tudor-knot	382..432	CDD:288553	9/51 (18%)
		NAT_SF	528..813	CDD:302625
		MOZ_SAS	599..778	CDD:280097
Samd1	NP_001074884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30		8/33 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..232		34/161 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	261..381		35/171 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	417..439
		SAM_Atherin-like	440..508	CDD:188982
		SAM	440..506	CDD:197735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900