Protein Alignment mof and kat6b

DIOPT Version :10

• Sequence 1: NP_511051.1
• Gene: mof / 31518
• FlyBaseID: FBgn0014340
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_697383.4
• Gene: kat6b / 568932
• ZFINID: ZDB-GENE-000607-52
• Length: 2044
• Species: Danio rerio
• Alignment Length: 898
• Identity: 245/898 - (27%)
• Similarity: 362/898 - (40%)
• Gaps: 218/898 - (24%)

  Fly    24 HEPEQEPTDAYTIG----GPPRTPVEDAAAELSASLDV--SGSDQSAEQSLDLSG---------- 72
            ||.:|...|...|.    |...:..:....||.:..|.  ||.....:.|.||:.
Zfish   203 HERDQPRADPIPICSFCLGTKESNRDKRPEELLSCADCGSSGHPSCLKFSADLTANVKALRWQCI 267

  Fly    73 ---------VQAEAAAE---------------SEPPAKRQHRD--ISPISEDSTPASSTSTSSTR 111
                     :|.:.|.|               .:||..|..:.  |..:..............|.
Zfish   268 ECKTCSSCQIQGKNADEMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKEQEGKRLLHKTA 332

  Fly   112 SSSSSRYDDVSEAEEAPPEPEPEQPQQQQQEEKKEDGQDQVKSPGPVELEAQEPAQPQKQKEVVD 176
            :....||            .:|.:|::........|      |.||..:|..|.|:..:
Zfish   333 AQIKRRY------------AKPGRPRKNLAHPTMSD------SGGPGSVELSEKARHGR------ 373

  Fly   177 QEIETE-DEPSSDTVICVADINPYGSGSNIDDFVMDPDAPPNAIITEVVTIPAPLHLKGTQQL-- 238
            ..|.|. ..|||.|.|      |...|.::.|        |......:.|:| |:: |.|:.|
Zfish   374 GSISTFCTPPSSSTFI------PTTDGRSLTD--------PLTSTPTLTTLP-PIN-KKTKGLID 422

  Fly   239 GLPLAAPPPPPPPPAAEQVPETPASPTDDGEEPPAVYLSPYIRSRYMQESTPGLPTRLAPRDPRQ 303
            ||.....|.|     ..:.....||.:.:...|    .....|..:....|||:  ||
Zfish   423 GLSKFFTPSP-----LGRRLRGEASGSSNQHRP----RKRGYRKHHASMMTPGV--RL------- 469

  Fly   304 RNMPPPAVVLPIQTVLSANVEAISDDSSETSSSDDDEEEEEDEDDALTMEHDNTSRETVITTGDP 368
             |.|...::.|..:...:.:......||..||:..              .|.::|:    ::|..
Zfish   470 -NAPSSVLLTPSPSQGHSPISLNPTQSSSPSSAHS--------------PHSSSSQ----SSGPS 515

  Fly   369 LMQKIDISENPDKIYFIRREDGTVH----RGQVLQS------------RTTENAAAP-------- 409
            |      |..|.........||..|    :||..|.            ||.:.:.:|
Zfish   516 L------SSLPGNSQLKGLFDGLSHIFTTQGQSRQKGLPSYAPPKRVRRTQDMSTSPKMSLQLQG 574

  Fly   410 ----DEYYVHYVGLNRRLDGW-------------------VGRHRISDNADDLGGITVLPAPPLA 451
                ..:......|.....||                   :.:|::      ||......:|...
Zfish   575 KKPVKGFCSKLASLASSASGWPPKRGRPFKSALHFKRTPILRKHKL------LGRFRFKASPQRE 633

  Fly   452 PDQPSTSREMLAQQAAAAAAASSERQKRAANKDYYLSYCENSRYDYSDRKMTRYQKRRYDE---- 512
            ...|...|            .:..|.|...|..:.:..|  .|.:..:.:||.......:|
Zfish   634 NITPGKGR------------LADGRVKPDPNHAFNVERC--LRREPQEGRMTLVNDHVAEEDLKL 684

  Fly   513 INHVQKSHAELTATQAALEKEHESITKIKYIDKLQFGNYEIDTWYFSPFPEEYGKARTLYVCEYC 577
            ..||:    ||||.:...::....       ..::||.|||.|||.||:|.||.:...||:||:|
Zfish   685 FRHVK----ELTAKKNGGDQGQSP-------PLIEFGKYEIQTWYSSPYPPEYLRLPKLYLCEFC 738

  Fly   578 LKYMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKLFLDHKVLYF 642
            ||||:.:.....|..:|....||..|||||.|:|::||:|....::||.|||:||||||||.||:
Zfish   739 LKYMKSQDILQRHSKKCGWFHPPANEIYRKDNLSVFEVDGNISKIFCQNLCLLAKLFLDHKTLYY 803

  Fly   643 DMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIAFSYELSRKE 707
            |::|||||:|.:.|::|.|:||||||||...:.|||:||:::|..||:|||:.||.|||.|||.|
Zfish   804 DVEPFLFYVLTQNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQFQRQGFGRFLIDFSYLLSRLE 868

  Fly   708 GVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPEQ-ITIKELSEMSGITHDDIIYTLQSMKM 771
            |..|||||||||||||||.:||...:||.:...  |:: ::|:.:|..:|:...||..|||.:.|
Zfish   869 GQAGSPEKPLSDLGRLSYLAYWKSVILEYLHNH--PDKSVSIRGMSRATGMCPHDIATTLQQLNM 931

  Fly   772 IKYWKGQNVICVTSKTIQDHLQLPQFKQPKL-TIDTDYLVWSPQTAAAVVRAP 823
            |.:..|:.||....:.|::|:...:.| |:| .:|.|.|.|:|   |.|.|:|
Zfish   932 IDFQDGRFVIIQRHQLIEEHMDRLRVK-PRLHEVDPDCLSWTP---ALVCRSP 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	PLN00104	387..813	CDD:215056	164/478 (34%)
kat6b	XP_697383.4	H15	113..167	CDD:197772
		PHD_SF	212..270	CDD:473978	10/57 (18%)
		PHD2_KAT6A_6B	271..317	CDD:277002	7/45 (16%)
		PLN00104	<674..973	CDD:215056	139/312 (45%)
		PRK10263	<1834..>1943	CDD:236669