DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mof and kat7

DIOPT Version :9

Sequence 1:	NP_511051.1	Gene:	mof / 31518	FlyBaseID:	FBgn0014340	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	XP_012827190.1	Gene:	kat7 / 548673	XenbaseID:	XB-GENE-488776	Length:	617	Species:	Xenopus tropicalis

Alignment Length:	767	Identity:	221/767 - (28%)
Similarity:	329/767 - (42%)	Gaps:	202/767 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 PISEDSTPASSTSTSSTRSSSSSRYDDVSEAEEAPPEPEPEQPQQQQQEEKKEDGQDQVKSPGPV 158
            |..:.:..:||..|..:..|:...:.|.||:                      ||    .|.||.
Frog     2 PRRKRNAGSSSDGTEDSDFSTDMEHTDSSES----------------------DG----NSRGPA 40

  Fly   159 ELEAQEPAQPQKQKEVVDQEIETEDEPSSDTVICVADINPYGSGSNIDDFVMDPDAPPNAIITEV 223
            .:........|..:                      |.:|.|   |:..|    .|......|..
Frog    41 RVTRSTARLSQSSQ----------------------DSSPVG---NLQSF----GAEEPVYSTRR 76

  Fly   224 VTIPAPLHLKGTQQLGLPLAAPPPPPPPPAAEQVPETPASPTDDGEEPPAVYLSPYIRSRYMQES 288
            ||       :..||         |.|..|....:.:|.:|.::..:........|. .:.|..||
Frog    77 VT-------RSQQQ---------PTPVTPKKYPLRQTRSSGSETEQAVDFCDRDPK-NAGYHDES 124

  Fly   289 TPGLPTRLAPRDPRQRNMPPPAVVLPIQTVLSANVEAISDDSSETSSSDDDEEEEE--------- 344
            .|..||..||......::..|.|         ::.|:|:.|.|...|..|.....:
Frog   125 PPRTPTGNAPSSESDIDISSPNV---------SHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN 180

  Fly   345 ----------DEDDALTMEHDNTSRETVITTGDPLMQKIDISENPDKIYFIRREDGTVHRGQVLQ 399
                      :....||.:|:   |...| :|.||...:...|
Frog   181 FNMKCPTPGCNSLGHLTGKHE---RHFSI-SGCPLYHNLSADE---------------------- 219

  Fly   400 SRTTENAAAPDEYYVHYVGLNRRLDGWVGRHRISDNADDLGGITVLPAPPLAPDQPSTSREMLAQ 464
               .:|.   ||:.|.....:::::..:..||..:|                            .
Frog   220 ---CKNC---DEFQVRAQSRDKQVEDRMLSHRQDEN----------------------------N 250

  Fly   465 QAAAAAAASSERQKRAANKDYYLSYCENSRYDYSDRKMTRYQKRRYDEINHVQ------------ 517
            :.|....|.:|||.|...|...|....||       .:|:.||.:|.|  |.|
Frog   251 RHATRHQAPTERQLRYKEKVTELRKKRNS-------GLTKEQKEKYME--HRQTYGDTREPLLEN 306

  Fly   518 -KSHAELTATQAALEKEHESITKIK----------YIDKLQFGNYEIDTWYFSPFPEEYGKARTL 571
             .|..:|...:.|..:..:.:.|::          .|..:.||.||:||||.||:||||.:...|
Frog   307 LTSEYDLELFRRAQARASDDLEKLRLQGQITEGSNMIKTIIFGRYELDTWYHSPYPEEYARLGRL 371

  Fly   572 YVCEYCLKYMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKLFLD 636
            |:||:|||||:.::....|:.:|..:.|||.||||||:||::||:||:..:|||.|||:||||||
Frog   372 YMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLD 436

  Fly   637 HKVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIAFSY 701
            ||.||:|::|||||::.|.|..|.|::|||||||.|..||||:|||.:|.:.|:|:||:||.|||
Frog   437 HKTLYYDVEPFLFYVMTEGDNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSY 501

  Fly   702 ELSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPEQITIKELSEMSGITHDDIIYTL 766
            .||:.|..:||||:||||||.:||||||...||..:. ....::|:|||:|:.:.:...||:.||
Frog   502 LLSKVEDKVGSPERPLSDLGLISYRSYWKEVLLRYLH-NFQGKEISIKEISQETAVNPVDIVSTL 565

  Fly   767 QSMKMIKYWKGQNVICVTSKTIQDHLQLPQFKQPK-----LTIDTDYLVWSP 813
            |:::|:|||||::::......|.:...    |..|     .|:|...|.|:|
Frog   566 QALQMLKYWKGKHLVLKRQDLIDEWAS----KDAKRTNSNKTMDPSCLKWTP 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	Tudor-knot	382..432	CDD:288553	5/49 (10%)
		NAT_SF	528..813	CDD:302625	138/299 (46%)
		MOZ_SAS	599..778	CDD:280097	102/178 (57%)
kat7	XP_012827190.1	zf-C2HC	184..212	CDD:366692	7/31 (23%)
kat7	XP_012827190.1	PLN00104	<323..615	CDD:215056	138/296 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D285390at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010