Protein Alignment mof and Kat6b

DIOPT Version :10

• Sequence 1: NP_511051.1
• Gene: mof / 31518
• FlyBaseID: FBgn0014340
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_006519326.1
• Gene: Kat6b / 54169
• MGIID: 1858746
• Length: 2054
• Species: Mus musculus
• Alignment Length: 704
• Identity: 206/704 - (29%)
• Similarity: 311/704 - (44%)
• Gaps: 129/704 - (18%)

  Fly   181 TEDEPSSDTVICVADINPYGSGSNIDDFVMDPDAPPNAIITEVVTIPAPLHLKGTQQLGLPLAAP 245
            |.||.|.....        |.||           |.....|:|.|.|:..|....:.....||..
Mouse   358 TSDEGSMSAFT--------GRGS-----------PGRGQKTKVSTTPSSGHAASGKHSSSRLAVT 403

  Fly   246 PPPPPPPAAEQVPETP-----------------------ASPTDDGEEP--PAVYLSPYIRSRYM 285
            .|..|....:....:.                       .:|:.||...  ..:..|.:.|.|..
Mouse   404 DPTRPGATTKTTTSSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKK 468

  Fly   286 QESTPGLPTRLAPRDPRQRNMPPPAVVLPIQTV--LSANVEAISDDSSETSSSDDDEEEEEDEDD 348
            ........:.:......|:..|.|:.:||...:  .|.:.:..|..:|.||:.....:..|....
Mouse   469 VSQKQSCTSHVLATGTTQKLKPAPSALLPPAPISGQSPSSQKSSSSTSSTSTQSSSSQSGEPSFS 533

  Fly   349 ALT-----------MEHDNTSRETVITTGDP-------LMQKIDISENPD-KIYFIRRED----- 389
            :||           :.|..|::......|.|       :.:|.:.|.... |..|..:.|
Mouse   534 SLTNNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTEFSSTAKAKARFFGKRDFRSRL 598

  Fly   390 -------GTVHRGQVLQS-----RTTENAAAPDEYYVHYVGLNRRLDGWVGRHRISDNADDLGGI 442
                   ..:.||.:.::     |||                      ::.:||:      ||.:
Mouse   599 LSHSSCSWGMTRGHIFKAIAHFKRTT----------------------FLKKHRM------LGRL 635

  Fly   443 TVLPAPPLAPDQPSTSREMLAQQAAAAAAASSERQKRAANKDYYLSYCENSRYDYSDRKMTRYQK 507
            .....|.:.  .||:.:..||.     ...:.::..   :.|..:|..:.|    :|..:...::
Mouse   636 KYKVTPQMG--TPSSGKGSLAD-----GRINPDQDN---DTDIKISIKQES----ADVSLVGNKE 686

  Fly   508 RRYDEINHVQKSHAELTATQAALEKEHESITKIKYIDKLQFGNYEIDTWYFSPFPEEYGKARTLY 572
            ...:|...|.|...||:..:...|...|...  :|...::||.|||.|||.||:|:||.:...||
Mouse   687 LVTEEDLDVFKQAQELSWEKIECESGVEDCG--RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLY 749

  Fly   573 VCEYCLKYMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKLFLDH 637
            :||:|||||:.::....|..:|....||..||||:.::|::||:|....:|||.|||:|||||||
Mouse   750 LCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDH 814

  Fly   638 KVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIAFSYE 702
            |.||:|::|||||:|.:.|::|.|:||||||||...:.|||:||:::|.|||:|||:.||.|||.
Mouse   815 KTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYL 879

  Fly   703 LSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPEQITIKELSEMSGITHDDIIYTLQ 767
            |||:||..|||||||||||||||.:||...:||.: .|.....|:||.:|..:|:...||..|||
Mouse   880 LSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYL-YRHHERHISIKAISRATGMCPHDIATTLQ 943

  Fly   768 SMKMIKYWKGQNVICVTSKTIQDHLQ-LPQFKQPKLTIDTDYLVWSPQTAAAVV 820
            .:.||....|:.||....|.|..|:: |....:|. .:|.:.|.|:|...:..|
Mouse   944 HLHMIDRRDGRFVIIRREKLILGHMEKLKNCSRPN-ELDPESLRWTPMLISNAV 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	PLN00104	387..813	CDD:215056	160/443 (36%)
Kat6b	XP_006519326.1	H15	94..168	CDD:197772
		PHD1_MOZ_MORF	213..270	CDD:277090
		PHD2_KAT6A_6B	272..318	CDD:277002
		PLN00104	<721..989	CDD:215056	133/269 (49%)