DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mof and kat5b

DIOPT Version :9

Sequence 1:	NP_511051.1	Gene:	mof / 31518	FlyBaseID:	FBgn0014340	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	XP_021331810.1	Gene:	kat5b / 503731	ZFINID:	ZDB-GENE-030131-985	Length:	555	Species:	Danio rerio

Alignment Length:	506	Identity:	179/506 - (35%)
Similarity:	262/506 - (51%)	Gaps:	105/506 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 YYVHYVGLNRRLDGWVGRHRI-------------SDNADDLGG-----------------ITVLP 446
            |||||:..|:|||.||...|:             :...:.|.|                 :....
Zfish    44 YYVHYIDFNKRLDEWVTPDRLDLKKLQFPKKEAKTPTKNGLPGSRPSSPEREVRKSLDLNVQSAS 108

  Fly   447 APPLAPDQPSTSRE----MLAQQAAAA--------AAASSERQKRAANKDYYLSYCENSRYDYSD 499
            ||......|:..|:    .||.|..||        :|.:|:.....|.:|...|......::...
Zfish   109 APSRGKTLPTPKRKAESVSLATQVTAATPVPSLPSSAEASQASVYPAMRDSSFSIKAREEHEQLT 173

  Fly   500 RKMTRYQKRRY---------------DEINHVQKSHAELTAT----------------------- 526
            ...|....||.               :||..|.::::..::|
Zfish   174 SLTTNGTTRRLIPSQPGRKRKNCVGTEEIVKVFQNNSPRSSTVYLPPGEDSQDSSDGIPSAPRMT 238

  Fly   527 -QAALEKEHES-ITKIKYIDKLQFGNYEIDTWYFSPFPEEYGKARTLYVCEYCLKYMRFRSSYAY 589
             ....::.|:. ||::|.||.::.|.:.:..|||||:|:|......||:||:||||::.......
Zfish   239 GSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQR 303

  Fly   590 HL-------------HE----CDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKLFLDH 637
            ||             |:    |:.|.|||.||||||.||.:|::|::..:|.|.|||:||.||||
Zfish   304 HLVRAVLGPDVTHSQHQIKTKCNLRHPPGNEIYRKGTISFFEIDGRKNKMYSQNLCLLAKCFLDH 368

  Fly   638 KVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIAFSYE 702
            |.||:|.||||||::.|.|.:|.||||||||||:|.|:|||||||.|||:||:|:|||||.||||
Zfish   369 KTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYE 433

  Fly   703 LSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPE----QITIKELSEMSGITHDDII 763
            ||:.||..|:|||||||||.|||||||:.|:||::....:..    |:||.|:||::.:..:|:|
Zfish   434 LSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMNLKSENGERPQMTINEISEITSVKKEDVI 498

  Fly   764 YTLQSMKMIKYWKGQNVICVTSKTIQDHLQLPQFKQPKLTIDTDYLVWSPQ 814
            .|||.:.:|.|:|||.::.::...::.|.:  ...:..|.||:..|.::|:
Zfish   499 STLQYLNLINYYKGQYILTLSEDIVEGHER--AMHKRHLRIDSKCLHFTPK 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	Tudor-knot	382..432	CDD:288553	11/19 (58%)
		NAT_SF	528..813	CDD:302625	143/306 (47%)
		MOZ_SAS	599..778	CDD:280097	109/182 (60%)
kat5b	XP_021331810.1	Tudor-knot	8..66	CDD:314560	12/21 (57%)
kat5b	XP_021331810.1	MOZ_SAS	<243..546	CDD:332306	143/304 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D285390at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100632
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R415
SonicParanoid	1	1.000	-	-		X828
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750