Protein Alignment mof and lsy-12

DIOPT Version :10

• Sequence 1: NP_511051.1
• Gene: mof / 31518
• FlyBaseID: FBgn0014340
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001263849.1
• Gene: lsy-12 / 3565873
• WormBaseID: WBGene00045419
• Length: 1585
• Species: Caenorhabditis elegans
• Alignment Length: 896
• Identity: 216/896 - (24%)
• Similarity: 342/896 - (38%)
• Gaps: 217/896 - (24%)

  Fly    11 SAGHVQEQPIEEEHEPEQEPTDAYTIGGPPRTPVEDAAAELSASLD--------VSGSDQ---SA 64
            |...::.:|::.:::...:|       ||...||       ||..|        :....|   |.
 Worm    61 SLERIKREPVDTDYDDPNQP-------GPSSVPV-------SARTDHVLPIRFKIKAEPQEYDSD 111

  Fly    65 EQSLDLSGVQAEAAAESEPPAKRQHRDISPISEDSTPASSTSTSSTRSSSSSR---YDDVSEAEE 126
            |...|...||   .|..|.||      ||||.|    .|.......|.:.:::   :..||..:
 Worm   112 EYGKDHGAVQ---IANKEVPA------ISPIEE----VSQKRRGRPRKTDAAQHLFFPHVSIKQ- 162

  Fly   127 APPEPE--------------PEQPQQQQQEEKKEDGQDQVKSPGPVELEAQEPAQPQKQKEVVDQ 177
               ||:              .:.|:.|...:..|....::    .:..|.::..:.:|:|
 Worm   163 ---EPDDGFINFHESRCVGIAQDPEMQHLHDVNESHSSEI----AIFRETKKITERKKKK----- 215

  Fly   178 EIETEDEPSSDTVICVADINPYGSGSNIDDFVMDPDAPPNAIITEVVTIPAPLHLKGTQQLGLPL 242
               ||.|...|                            |..:||.....:  |.:..:...||:
 Worm   216 ---TEAEKLWD----------------------------NMSLTEKEVFQS--HTRRRRTTRLPI 247

  Fly   243 AAPPPPPPPPAAEQVP------ETPASPTDDGEEPPAVYLSPYIRSRYMQESTPGLPTRLAPRDP 301
            .............:||      :..|..:..|.:...|.:|..:.|   .|||....|.......
 Worm   248 IQNFEETEEGCIVEVPIPLIDLDNDAVESVTGPQHENVTVSENVLS---TESTDQEVTETKRLHD 309

  Fly   302 RQRNMPPPAVVLPIQTVLSANVEAISDDSSETSSSDDDEEEEEDEDDALTMEHDNTSRETVITTG 366
            ..|:..||.    ||...|..:....|.....||:........:...|..:.:.::   |.:|.
 Worm   310 SSRDFNPPR----IQDTPSTVIRPEGDQKDPMSSTSSKRRNTNNSRCASLLSNPHS---TPVTR- 366

  Fly   367 DPLMQKIDISENPDKIYFIRREDGTVHRGQVLQSRTTENAAAPDEYYVHYVGLNRRLDGWVGRHR 431
              ||:.|..|||.|....:..:...:.:    :.||.....:|:        ..||.:..:....
 Worm   367 --LMRGILDSENSDNDEMLSNDQSEIAK----RPRTPRPRYSPE--------AQRRTNSRLSALT 417

  Fly   432 ISDN-ADDLGGITVLPAPPLA-------PDQPSTSRE-MLAQQAAAAAAASSERQKRAANKDYYL 487
            |..| ::||......|:...|       ||...||:: ....|:||.:..........:.:|
 Worm   418 IDTNRSNDLNVDGSAPSSSSAASCGLSTPDPDRTSQQRRKGNQSAARSRKIKTPSPPLSQED--- 479

  Fly   488 SYCENSRYDYSDRKMTRYQKRRYDEINHVQKSHAELTATQAALEKEHESI--------------- 537
               |....|..|           |.:|.:......:......|.|||:.|
 Worm   480 ---EPMELDSDD-----------DPVNELDNLPIVIDDPSYVLTKEHKEIFEQVKKSVSDRNEFS 530

  Fly   538 -TKIKYI------------DKLQFGNYEIDTWYFSPFPEEYGKARTLYVCEYCLKYMRFRSSYAY 589
             .:|..|            :::.||.:.:.|||.||||.|:...:.|::||:|..|.|.......
 Worm   531 PAQISEIYRSSKGEQARLPERIHFGAFIMKTWYGSPFPAEFINVKKLFICEFCFFYARSDEIMQN 595

  Fly   590 HLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKLFLDHKVLYFDMDPFLFYILCE 654
            |..:|..|.|||.||||||:||::||:|:.:..|||.|||::::||:.|.:::|.:||.|||:..
 Worm   596 HAKKCMLRAPPGLEIYRKGDISVFEVDGRLQKEYCQTLCLVSRMFLESKTVFYDTEPFFFYIVTI 660

  Fly   655 TDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIAFSYELSRKEGVIGSPEKPLSD 719
            .|..|.|..|||||||...:..|::||:.||.:|..|.|:.||..||.|||||...|.||:|||:
 Worm   661 NDDIGCHFAGYFSKEKYEPDVNNLSCIMTLPCYQEMGLGRFLIDISYALSRKEKWFGGPEQPLSE 725

  Fly   720 LGRLSYRSYWAYTLLELMKTRCAPE-----QITIKELSEMSGITHDDIIYTLQSMKMIK------ 773
            |||.:|..||..|:...: .|...|     .|:||.:::.:|:...||:..:.|:...|
 Worm   726 LGRKAYGGYWRTTIASCL-GRLKDELEFGSGISIKMIADDTGVNCHDILEVVCSLGWAKPVDPDE 789

  Fly   774 ---Y-------WKGQNVICVTSKTIQDHLQLPQFKQPKLTIDTDYLVWSPQ 814
               |       |...::|...|:.         .|:.|:..|.:.|.|.|:
 Worm   790 KNHYKLEWDVDWDMVSIILRESEA---------SKETKVQYDPECLDWVPR 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	PLN00104	387..813	CDD:215056	138/483 (29%)
lsy-12	NP_001263849.1	zf-MYST	547..600	CDD:407644	17/52 (33%)
		MOZ_SAS	605..786	CDD:460362	79/181 (44%)