DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mof and kat8

DIOPT Version :9

Sequence 1:	NP_511051.1	Gene:	mof / 31518	FlyBaseID:	FBgn0014340	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_997907.1	Gene:	kat8 / 100003790	ZFINID:	ZDB-GENE-030131-7510	Length:	487	Species:	Danio rerio

Alignment Length:	494	Identity:	244/494 - (49%)
Similarity:	328/494 - (66%)	Gaps:	66/494 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 SSETSSSDDDEEEEEDEDDALTMEHDNTSRETVITTGDPLMQKIDISENPDKIYFIRREDGTVHR 394
            ||..|..::||.|..|.:...|......|.:.|...|.   ::.::|....:.|..:|.|.|.|.
Zfish    39 SSNGSGGEEDEMEAADREREATGSSTPRSADGVSLGGG---REQEVSVEIGETYLCQRTDKTWHS 100

  Fly   395 GQVLQSRTTENAAAPDEYYVHYVGLNRRLDGWVGRHRIS----------DNADDLGGITVLPAPP 449
            .:|:|||..|.... :|:||||||.|||||.|||:.|::          .:.::.||..::
Zfish   101 AEVIQSRLNEQEGR-EEFYVHYVGFNRRLDEWVGKARLALTKTVKDAVRKSVEEGGGGELV---- 160

  Fly   450 LAPDQPSTSREMLAQQAAAAAAASSERQKRAANKDYYLSYCENSRYDYSDRKMTRYQKRRYDEIN 514
               |||                                           :||:||.|||::||||
Zfish   161 ---DQP-------------------------------------------ERKITRNQKRKHDEIN 179

  Fly   515 HVQKSHAELTATQAALEKEHESITKIKYIDKLQFGNYEIDTWYFSPFPEEYGKARTLYVCEYCLK 579
            ||||::||:..|.||||||||:|||:||:||:|.||:|||.||||||||:|||...|::||||||
Zfish   180 HVQKTYAEMDPTTAALEKEHEAITKVKYVDKIQIGNFEIDAWYFSPFPEDYGKQPKLWICEYCLK 244

  Fly   580 YMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKLFLDHKVLYFDM 644
            ||::..::.|||.:|..|:|||:|||||.|||:|||:||:..:|||.|||:||||||||.||||:
Zfish   245 YMKYEKTFRYHLSQCQWRQPPGKEIYRKNNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDV 309

  Fly   645 DPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIAFSYELSRKEGV 709
            :||:||||.|.:|:|:||||||||||:|.:..||||||.|||:||:|:||.|||||||||:.|..
Zfish   310 EPFIFYILTEVNKQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLEST 374

  Fly   710 IGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPEQITIKELSEMSGITHDDIIYTLQSMKMIKY 774
            :|||||||||||:|||||||::.|||::  |.....::||:||:|:.||..|||.|||.:.|:||
Zfish   375 VGSPEKPLSDLGKLSYRSYWSWVLLEIL--RDFRGTLSIKDLSQMTSITQSDIISTLQPLNMVKY 437

  Fly   775 WKGQNVICVTSKTIQDHLQLPQFKQPKLTIDTDYLVWSP 813
            ||||:|||||.|.:::||:..|:|:|.:|:||..|.|:|
Zfish   438 WKGQHVICVTPKLVEEHLKSAQYKKPPITVDTHCLKWAP 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	Tudor-knot	382..432	CDD:288553	25/49 (51%)
		NAT_SF	528..813	CDD:302625	182/284 (64%)
		MOZ_SAS	599..778	CDD:280097	118/178 (66%)
kat8	NP_997907.1	PLN00104	31..478	CDD:215056	244/494 (49%)
		Tudor-knot	83..139	CDD:288553	26/56 (46%)
		NAT_SF	189..456	CDD:302625	174/268 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577973
Domainoid	1	1.000	262	1.000	Domainoid score	I1915
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41676
Inparanoid	1	1.050	468	1.000	Inparanoid score	I1492
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D285390at33208
OrthoFinder	1	1.000	-	-		FOG0005248
OrthoInspector	1	1.000	-	-		oto41505
orthoMCL	1	0.900	-	-		OOG6_100632
Panther	1	1.100	-	-	LDO	PTHR10615
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X828
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.760