Protein Alignment GAA1 and gpaa1

DIOPT Version :9

• Sequence 1: NP_572273.2
• Gene: GAA1 / 31517
• FlyBaseID: FBgn0029818
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_005171175.1
• Gene: gpaa1 / 555496
• ZFINID: ZDB-GENE-131121-587
• Length: 615
• Species: Danio rerio
• Alignment Length: 664
• Identity: 210/664 - (31%)
• Similarity: 325/664 - (48%)
• Gaps: 74/664 - (11%)

  Fly     1 MGLLSDPSISTQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFNHGTYLSENALSPGLVYPE 65
            |||||||  :.:..|.:.|.|....:|...|:|.:.||..||...|...||:||||:...:|  |
Zfish     1 MGLLSDP--NRRKALTNLLTRLNTPICVVCYLAAIVWFMGLAFEPFTLRTYMSENAMGSTMV--E 61

  Fly    66 IRIDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPF-GGGKEYH--- 126
            .|..|...|:...:|....:: .....|..|:...|...|||..|.::..:.|| ...||.:
Zfish    62 ERFSAGERALAAAKEFNAHKR-KADGMPVEWLVKAMQARGLEVFTQSFFQKLPFPDENKERYMVR 125

  Fly   127 GKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLLLAFADFARRKNYWAKDLIFLITE 191
            |.|:||||||||...||.:|.:||.....:    .:.:|.:||..|.:.|.:.|||||:|||:.|
Zfish   126 GTNVYGILRAPRAPRTEALVISAPCTPGGT----NNQAVGILLGLAQYFRNQVYWAKDIIFLVNE 186

  Fly   192 QEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEVQDLEIDHVDVRIEGLNGK 256
            .:.:|||||||.||    ..:::.....|  |..||||:||||::|:....|..:|:.:|||||:
Zfish   187 HDLIGMQAWLEGYH----HTNITGMEYSP--LQGRAGSIQAALSLELSSDVITSLDLVLEGLNGQ 245

  Fly   257 LPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQNFRQMLTMLASQSSGVPTGNHGLFH 321
            |||||:.||......:..:....:...::....|...:....:.|:.|:..|:||...|:||||.
Zfish   246 LPNLDLANLFYAFCQKLNVLCTIQGKLQRNDWDSAEGYTHAAQTMMLMVLKQASGRSWGDHGLFL 310

  Fly   322 RYRIDALTIAANRRATHATLKGSPGSAAVPLLKAIEGIARSLNNLLERFHQSFFFYVIVSNDRYI 386
            ||.|:|.:|.......|..:.      |..:.:.:||:.|.|||||||.|||:|||::.|..|::
Zfish   311 RYHIEAASIRGINSFRHYKMD------ATTIGRLLEGMVRKLNNLLERLHQSYFFYLLPSLSRFV 369

  Fly   387 SIGDYMPALVALVACAFLKAYLTWSTLPATNAELEKAAGWLREHEQEAELEENLEPDKFELPYGS 451
            |||.||||...|.....|:|...|..|         .|..|.|.:..:|.|:...|...     |
Zfish   370 SIGYYMPAFGLLAVILLLRALDLWVHL---------GAPVLSEVDGVSEAEQPSSPGVL-----S 420

  Fly   452 VLIYLTATLLIGFLCNVLPLQQYFLEIPMGAAPLTTS---VLSFLSL--IGFVLPFVV--VLPPG 509
            ||..:..:.|.|....:||:  |..::.:...|::.:   ||:.|::  .|..||...  :|...
Zfish   421 VLTPVVISHLTGVALYILPV--YLQDMAVEHFPVSETEAVVLTALAIYTAGLALPHNTQRLLSGE 483

  Fly   510 GLE----------LLHVAFLLIYGCALIVIGLLNFALGLFAAVLTVPLVIALETKEENSRSTLRN 564
            |.|          ||::|.||  ||.    .|:||:||...||..||:..::      :...|::
Zfish   484 GTEQGWKVLKLTSLLYLAVLL--GCT----ALINFSLGFILAVTLVPVTASI------TPHMLKS 536

  Fly   565 TIRLATLVMNPMMVVYVIVLAMTFYQFPELPVQKIMLRAATAAMDASAYGLIDSVIYGNWLYFVI 629
            ...||.::::|...::..||  .:.:..|.||.  :....|..:...:.|::|..:||:.:|.::
Zfish   537 VSALAMVLLSPAFTIFYCVL--IYQELMEAPVS--LPEGLTIFLSVISQGILDHALYGSLVYPLL 597

  Fly   630 CTIFLPLWIICWTL 643
            .....|.|::.|.:
Zfish   598 ALFVYPCWLMFWNI 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAA1	NP_572273.2	Gaa1	127..639	CDD:282032	168/528 (32%)
gpaa1	XP_005171175.1	Gaa1	126..607	CDD:282032	168/528 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579741
Domainoid	1	1.000	229	1.000	Domainoid score	I2412
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37852
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2892
OMA	1	1.010	-	-		QHG46078
OrthoDB	1	1.010	-	-		D1486030at2759
OrthoFinder	1	1.000	-	-		FOG0005054
OrthoInspector	1	1.000	-	-		oto39041
orthoMCL	1	0.900	-	-		OOG6_104164
Panther	1	1.100	-	-	LDO	PTHR13304
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R467
SonicParanoid	1	1.000	-	-		X3579
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900