Protein Alignment GAA1 and gpaa1

DIOPT Version :9

• Sequence 1: NP_572273.2
• Gene: GAA1 / 31517
• FlyBaseID: FBgn0029818
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001015809.1
• Gene: gpaa1 / 548526
• XenbaseID: XB-GENE-974957
• Length: 615
• Species: Xenopus tropicalis
• Alignment Length: 675
• Identity: 204/675 - (30%)
• Similarity: 318/675 - (47%)
• Gaps: 96/675 - (14%)

  Fly     1 MGLLSDPSISTQSKLVDGLARHVRK----VCYALYVAGVAWFFCLALPEFNHGTYLSENALSPGL 61
            |||||||:..      ..|:|.|.:    :|...|:.|..||..||...|...:|:|||::...:
 Frog     1 MGLLSDPNRR------QALSRVVTQLNTPLCIISYLVGTMWFLGLAFQPFTLRSYISENSMGSTM 59

  Fly    62 VYPEIRIDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNY--TLRYPFGGGKE 124
            |  |.:..:....:....|....:|. ...:|.||:...|...|||.::.::  ||.:|....:.
 Frog    60 V--EEQFVSGERGLSYAREFAAHKKS-AGGSPVAWLERTMRGLGLEVYSQSFVRTLPFPDETTER 121

  Fly   125 Y--HGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLLLAFADFARRKNYWAKDLIF 187
            :  .|.|:||||||||.||||.:|.:.|    .|...:.:.:|.||||.|.:.|.:.|||||:||
 Frog   122 FMVKGTNVYGILRAPRAASTESLVLSVP----CSEGQNNNQAVGLLLALASYFRGQIYWAKDIIF 182

  Fly   188 LITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEVQDLEIDHVDVRIEG 252
            |:.|.:.:||:||||.||      |::...::...:..|||::|||:::|:....|...|:.:||
 Frog   183 LVNEHDLIGMEAWLEGYH------DVNVTEIKSSVMLGRAGAIQAAVSLEMSSDVITSFDLVVEG 241

  Fly   253 LNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQNFRQMLTMLASQSSGVPTGNH 317
            |||:|||||:.||......:..:....:...::....:...:..:.:.||.|:..|.||.|.|:|
 Frog   242 LNGQLPNLDLVNLFYAFCQKNTLLCTIQGKLQRTDFDTFPGYLHSLQTMLIMMLKQGSGRPQGDH 306

  Fly   318 GLFHRYRIDALTI-AANRRATHATLKGSPGSAAVPLLKAIEGIARSLNNLLERFHQSFFFYVIVS 381
            |||.||.|:|:|: ..|....:.....:.|       |.:||:.|.||||.||.|||:|||::..
 Frog   307 GLFLRYHIEAITLRGINSFRQYKYDMNTVG-------KTLEGMFRKLNNLSERLHQSYFFYLLPC 364

  Fly   382 NDRYISIGDYMPALVALVACAFLKAYLTWSTLPATNAELEKAAGWLREHEQEAELEENLEPDKFE 446
            ..|::|||.||||:...:....|::...|..|..::...|...         .:.|::..|....
 Frog   365 LSRFVSIGIYMPAIGFFILILILRSLDLWIKLRRSDGTAEDGV---------MDTEQDPRPGILS 420

  Fly   447 LPYGSVLIYLTATLLIGFLCNVLPLQQYFL-----EIPMGAAPLTTSVLSFLSLI-----GFVLP 501
            |          ||.::  :|:...|..|:|     |:.....|::.|....|:.|     |..||
 Frog   421 L----------ATPIV--ICHATGLSLYYLPVMSQEMATDHFPVSESEAVVLTAIAIYVAGLALP 473

  Fly   502 FVV--VLPPGG----------LELLHVAFLLIYGCALIVIGLLNFALGLFAAVLTVPL-VIALET 553
            ...  ||...|          :.||::|.||  ||    |.|:||:||...||..||: .|...|
 Frog   474 HNTHRVLSGAGSDQGWMTLKLISLLYLAVLL--GC----ISLINFSLGFLLAVTIVPVAAIVQPT 532

  Fly   554 KEENSRSTLRNTIRLATLVMNPMMVVYVIVLAMTFYQFPELPVQKIMLRAATAAMDASAYGLIDS 618
            ......:.|...|..||.::..:.:         :.:..|.||.  :|......:.|.|.|::|.
 Frog   533 GPRALYALLLVLITPATTLLGSIFL---------YRELIEYPVS--LLECWQLFLQAIAGGMLDH 586

  Fly   619 VIYGNWLYFVICTIFLPLWIICWTL 643
            .:||:.|:..|.....|.|:..|.:
 Frog   587 YLYGSLLFPFIAFFVYPCWLQLWNV 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAA1	NP_572273.2	Gaa1	127..639	CDD:282032	167/535 (31%)
gpaa1	NP_001015809.1	Gaa1	126..609	CDD:367824	167/537 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	215	1.000	Domainoid score	I2677
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37852
Inparanoid	1	1.050	245	1.000	Inparanoid score	I3215
OMA	1	1.010	-	-		QHG46078
OrthoDB	1	1.010	-	-		D1486030at2759
OrthoFinder	1	1.000	-	-		FOG0005054
OrthoInspector	1	1.000	-	-		oto104423
Panther	1	1.100	-	-	LDO	PTHR13304
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R467
SonicParanoid	1	1.000	-	-		X3579
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110