DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12729 and Psmf1

DIOPT Version :9

Sequence 1:	NP_572271.1	Gene:	CG12729 / 31515	FlyBaseID:	FBgn0029816	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001094475.1	Gene:	Psmf1 / 689852	RGDID:	1587528	Length:	271	Species:	Rattus norvegicus

Alignment Length:	170	Identity:	37/170 - (21%)
Similarity:	70/170 - (41%)	Gaps:	18/170 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 DLLIAVTHF-LITKEYRLRCAINYSASDGRQLAGGCGTVCEQLPDHWNRDADRYTLNY--TDGLA 120
            |.|:...|: ::|..|       |....|.| ........|.||..||.:.:.|.|.|  .|| |
  Rat    20 DALVCFLHWEVVTNGY-------YGLGTGDQ-PDPNDKKSELLPAEWNSNKELYALRYESKDG-A 75

  Fly   121 GQYILMAKLSRRDLVISLQNSTSKRMAIVCLQPEHLVNSTCKSSMDKCIPRLDKFIKRLRAELVD 185
            .:.:|.|......::|::....::::|.:.|..:..:::...|...:.....::...|:|:.::.
  Rat    76 RKLLLKAVSVENGMIINVLEHGTQQVADLTLNLDDYIDAEDLSDFHRTYKNSEELRSRIRSGIIT 140

  Fly   186 P------AVRGTKRLAEIGPAFNRKIWKRELPVRNSGTSR 219
            |      .||.:....|..||..|::....:...:..|||
  Rat   141 PIHEQWEKVRLSSPPREFPPATAREVDPLRISSHHPHTSR 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12729	NP_572271.1	PI31_Prot_N	50..193	CDD:288423	30/142 (21%)
Psmf1	NP_001094475.1	Important for homodimerization and interaction with FBXO7. /evidence=ECO:0000250	2..150		28/138 (20%)
		PI31_Prot_N	11..148	CDD:288423	28/136 (21%)
		PI31_Prot_C	182..248	CDD:285745
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350575
Domainoid	1	1.000	45	1.000	Domainoid score	I11876
eggNOG	1	0.900	-	-		E1_KOG4761
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1614691at2759
OrthoFinder	1	1.000	-	-		FOG0005143
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.800