Protein Alignment CG15765 and MRC2

DIOPT Version :10

• Sequence 1: NP_572269.1
• Gene: CG15765 / 31513
• FlyBaseID: FBgn0029814
• Length: 873
• Species: Drosophila melanogaster
• Sequence 2: NP_006030.2
• Gene: MRC2 / 9902
• HGNCID: 16875
• Length: 1479
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 60/277 - (21%)
• Similarity: 90/277 - (32%)
• Gaps: 87/277 - (31%)

  Fly     5 RCLVSFLGICLVISLGMRCDARAVNVSNTWTMPQEGLNVFYRFF-------RDRISWFEADAVCQ 62
            |||.:...||...::........:..:.....|.:.:....:.|       :.|:.|.||...|:
Human   941 RCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCE 1005

  Fly    63 FHHANLVTVDNSFQF--------DATRDLLRELDVNDIVWIGLMRPQNSDRFMWSNSRPLVADTG 119
            ...|.|||:.|..:.        :.|.||          ||||...|..  |.|....||:  ..
Human  1006 QQEAQLVTITNPLEQAFITASLPNVTFDL----------WIGLHASQRD--FQWVEQEPLM--YA 1056

  Fly   120 YWAESLPLMDAPL--------CAVI--DPIRDY--RWHALRCGGPETASFLCEM----------- 161
            .||...|...:|.        |||:  .|...:  ||....| ..||..|:|:.
Human  1057 NWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSC-TEETHGFICQKGTDPSLSPSPA 1120

  Fly   162 ---PVPS------------------WADACILKDMPNLTMQYMAD-------TASIELIRN---- 194
               |.|.                  |.||.:|.:..|.::.|:.|       |.:...:|.
Human  1121 ALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESRNASLAYVPDPYTQAFLTQAARGLRTPLWI 1185

  Fly   195 --CQEEGLLRHTCKGKE 209
              ..|||..|::...:|
Human  1186 GLAGEEGSRRYSWVSEE 1202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15765	NP_572269.1	CLECT	45..161	CDD:153057	38/142 (27%)
MRC2	NP_006030.2	beta-trefoil_Ricin_MRC2	42..165	CDD:467786
		FN2	180..228	CDD:128373
		CLECT	247..361	CDD:153057
		CLECT	382..505	CDD:214480
		CLECT	521..644	CDD:214480
		CLECT	669..809	CDD:214480
		CLECT	829..951	CDD:214480	4/9 (44%)
		CLECT	972..1108	CDD:214480	38/150 (25%)
		CLECT	1137..1245	CDD:153057	14/66 (21%)
		CLECT	1261..1394	CDD:214480
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1450..1479