DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R1 and PUP3

DIOPT Version :9

Sequence 1:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_011020.3	Gene:	PUP3 / 856830	SGDID:	S000000896	Length:	205	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	44/209 - (21%)
Similarity:	81/209 - (38%)	Gaps:	26/209 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PKAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLT 106
            |.:|..|. :|.:..||.|.:..|.|.....:.......||.| ..|::....|.|.|...:...
Yeast     4 PSSINGGI-VVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFH-YGHVFLGITGLATDVTTLNEM 66

  Fly   107 TSAELDLHRLNTERRV------PVVCASMMLRRTLFRYQGHIGAAL-------VMGGVDTTGPQL 158
            ...:.:|::|..||.:      .:|.:|:..||....:.|.:.|.:       .:.|.|..|
Yeast    67 FRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIG--- 128

  Fly   159 YCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDL 223
             ||     ::...:...|:.:.....:.|..::|:|:.|...:.:.:|:......|..||....:
Yeast   129 -CI-----DEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVV 187

  Fly   224 CVITAKGAV--YLR 235
            .:|.....|  ||:
Yeast   188 YIIKKDEVVKRYLK 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	42/203 (21%)
		proteasome_beta_type_7	49..236	CDD:239732	41/202 (20%)
		Pr_beta_C	241..274	CDD:289249
PUP3	NP_011020.3	proteasome_beta_type_3	8..201	CDD:239728	41/203 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810