DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R1 and PRE2

DIOPT Version :9

Sequence 1:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_015428.1	Gene:	PRE2 / 856218	SGDID:	S000006307	Length:	287	Species:	Saccharomyces cerevisiae

Alignment Length:	249	Identity:	68/249 - (27%)
Similarity:	108/249 - (43%)	Gaps:	37/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NTSADFVGLRSGFNFINCRRNAELLSKGYEPPKA---------------------IKTGTSIVGI 54
            |..:|||...|.|     :|.|..|:   .||.|                     |..||:.:..
Yeast    25 NLESDFVTGASQF-----QRLAPSLT---VPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAF 81

  Fly    55 IYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTE 119
            .::.|:|:..|:|||.|..|:.:...|:..:...:....||.|||.:.......::..||.|..:
Yeast    82 RFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREK 146

  Fly   120 RRVPVVCASMMLRRTLFRYQGHIGAALVMGGV-----DTTGPQLYCIYPCGSNDKIPYAAMGSGT 179
            .|:.|..||.:|...:::|:   ||.|.||.:     ...||.:|.:...|:..|.....:|||.
Yeast   147 ERISVAAASKILSNLVYQYK---GAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQ 208

  Fly   180 LAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDLCVITAKGAVY 233
            ..|..||:..:|.||.:|....|.:.:|.|....|..||.:::|..:|..|.:|
Yeast   209 TFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIY 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	55/191 (29%)
		proteasome_beta_type_7	49..236	CDD:239732	54/190 (28%)
		Pr_beta_C	241..274	CDD:289249
PRE2	NP_015428.1	proteasome_beta_type_5	76..264	CDD:239730	54/190 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810