DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R1 and PRE9

DIOPT Version :9

Sequence 1:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_011651.3	Gene:	PRE9 / 853036	SGDID:	S000003367	Length:	258	Species:	Saccharomyces cerevisiae

Alignment Length:	183	Identity:	47/183 - (25%)
Similarity:	85/183 - (46%)	Gaps:	17/183 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 YEPPKAIKT----GTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAAD 99
            |:...|:::    ||:| ||:..||::|.|:.:.|...:..|.:..|::.|.|.|....||..||
Yeast    20 YQVEYALESISHAGTAI-GIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTAD 83

  Fly   100 TEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQGH--------IGAALVMGGVDTT-G 155
            .|::..|.......:.......:||   .:::||.....||:        .|.:.:..|.|.. |
Yeast    84 AEILINTARIHAQNYLKTYNEDIPV---EILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYG 145

  Fly   156 PQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAIS 208
            .|||...|.|:.......::|:.|.||.::|:..:|.|:.::...:|..:.:|
Yeast   146 YQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLS 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	45/170 (26%)
		proteasome_beta_type_7	49..236	CDD:239732	44/169 (26%)
		Pr_beta_C	241..274	CDD:289249
PRE9	NP_011651.3	proteasome_alpha_type_4	4..216	CDD:239721	47/183 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810